D
Diane J. Hulse
Researcher at St. Jude Children's Research Hospital
Publications - 7
Citations - 993
Diane J. Hulse is an academic researcher from St. Jude Children's Research Hospital. The author has contributed to research in topics: Influenza A virus subtype H5N1 & Influenza A virus. The author has an hindex of 6, co-authored 7 publications receiving 980 citations. Previous affiliations of Diane J. Hulse include World Health Organization.
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Journal ArticleDOI
Evolution of H5N1 avian influenza viruses in Asia
Jean Thierry Aubin,Saliha Azebi,Amanda Balish,Jill Banks,Niranjan Bhat,Rick A. Bright,Ian Brown,Philippe Buchy,Ana Maria Burguiere,Hua Ian Chen,Peter K.C. Cheng,Nancy J. Cox,Alice Crosier,Aaron Curns,Frédérique Cuvelier,Guohua Deng,Julia Desheva,Stéphanie Desvaux,Nguyen Hong Diep,Ruben O. Donis,Ruben O. Donis,A. R. Douglas,Scott F. Dowell,Nguyen Tien Dung,Lindsay Edwards,Keiji Fukuda,Rebecca Garten,Elena A. Govorkova,Victoria Gregory,Alan W. Hampson,Nguyen Thi Hong Hanh,Scott A. Harper,A. Hay,Erich Hoffmann,Diane J. Hulse,Masaki Imai,Shigeyuki Itamura,Samadhan Jadhao,Patricia Jeannin,Chun Kang,Jackie Katz,Jae Hong Kim,Alexander Klimov,Yong Kuk Kwon,Chang-Won Lee,Phuong Song Lien,Yanbing Li,Wilina Lim,Yi Pu Lin,Stephen Lindstom,La Morris Loftin,Jan Mabry,Le Quynh Mai,Taronna R. Maines,Jean Claude Manuguerra,Masaji Mase,Yumi Matsuoka,Margaret McCarron,Marie-Jo Medina,Doan Nguyen,Ai Ninomiya,Masatsugu Obuchi,Takato Odagiri,Malik Peiris,Michael L. Perdue,Jean Marc Reynes,James Robertson,Claudine Rousseaux,Takehiko Saito,Somchai Sangkitporn,Michael W. Shaw,James Mark Simmerman,Marek J. Slomka,Catherine K. Smith,San Sorn,Erica Spackman,Klaus Stöhr,David L. Suarez,Haan Woo Sung,David E. Swayne,Maryse Tardy-Panit,Masato Tashiro,Pranee Thawatsupha,Terrence M. Tumpey,Timothy M. Uyeki,Phan Van Tu,Sylvie van der Werf,Sirenda Vong,Richard J. Webby,Robert G. Webster,John Wood,Xiyan Xu,Guan Yi,Wenging Zhang +93 more
TL;DR: Human infections were from a virus clade undergoing antigenic drift that showed resistance to adamantanes but sensitivity to neuraminidase inhibitors.
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Pathogenesis of Hong Kong H5N1 influenza virus NS gene reassortants in mice: the role of cytokines and B- and T-cell responses.
Aleksandr S. Lipatov,Samita Andreansky,Richard J. Webby,Diane J. Hulse,Jerold E. Rehg,Scott Krauss,Daniel R. Perez,Peter C. Doherty,Robert G. Webster,Mark Y. Sangster +9 more
TL;DR: In mice infected with reassortants containing the H5N1/97 NS gene, the mouse lethal dose and lung virus titres were similar to those of PR/8, which is highly pathogenic to mice, and this reassortant virus required two more days thanPR/8 to be cleared from the lungs of infected mice.
Journal ArticleDOI
Molecular Determinants within the Surface Proteins Involved in the Pathogenicity of H5N1 Influenza Viruses in Chickens
TL;DR: Analysis of H5N1 viruses constructed by reverse-genetic methods and containing recombinant HAs established that amino acids 97, 108, 126, 138, 212, and 217 of HA, in addition to those within the cleavage site, affect pathogenicity.
Journal ArticleDOI
Microbial adaptation and change: avian influenza.
Robert G. Webster,Diane J. Hulse +1 more
TL;DR: Strategies to reduce the evolution of influenza and the emergence of pandemics include the separation of species, increased biosecurity, the development of new vaccine strategies and better basic knowledge of the virus.
Journal ArticleDOI
Preparation of a standardized, efficacious agricultural H5N3 vaccine by reverse genetics.
Ming Liu,John Wood,Trevor M. Ellis,Scott Krauss,Patrick Seiler,Christie Johnson,Erich Hoffmann,Erich Hoffmann,Jennifer Humberd,Diane J. Hulse,Yun Zhang,Yun Zhang,Robert G. Webster,Daniel R. Perez,Daniel R. Perez +14 more
TL;DR: R reverse genetics allows the inexpensive preparation of standardized, efficacious H5N3 poultry vaccines that may also reduce the reemergence of H 5N1 genotypes.