T
Taronna R. Maines
Researcher at Centers for Disease Control and Prevention
Publications - 38
Citations - 3829
Taronna R. Maines is an academic researcher from Centers for Disease Control and Prevention. The author has contributed to research in topics: Virus & Influenza A virus. The author has an hindex of 18, co-authored 26 publications receiving 3627 citations. Previous affiliations of Taronna R. Maines include National Center for Immunization and Respiratory Diseases & World Health Organization.
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Journal ArticleDOI
Transmission and Pathogenesis of Swine-Origin 2009 A(H1N1) Influenza Viruses in Ferrets and Mice
Taronna R. Maines,Akila Jayaraman,Jessica A. Belser,Debra A. Wadford,Claudia Pappas,Hui Zeng,Kortney M. Gustin,Melissa B. Pearce,Karthik Viswanathan,Zachary Shriver,Rahul Raman,Nancy J. Cox,Ram Sasisekharan,Jacqueline M. Katz,Terrence M. Tumpey +14 more
TL;DR: In this paper, selected 2009 A(H1N1) influenza isolates were assessed for their ability to cause disease in mice and ferrets and compared with a contemporary seasonal H 1N1 virus for the ability to transmit to naive ferrets through respiratory droplets.
Journal ArticleDOI
A Two-Amino Acid Change in the Hemagglutinin of the 1918 Influenza Virus Abolishes Transmission
Terrence M. Tumpey,Taronna R. Maines,Neal Van Hoeven,Laurel Glaser,Alicia Solórzano,Claudia Pappas,Claudia Pappas,Nancy J. Cox,David E. Swayne,Peter Palese,Jacqueline M. Katz,Adolfo García-Sastre +11 more
TL;DR: These findings confirm an essential role of hemagglutinin receptor specificity for the transmission of influenza viruses among mammals and suggest that a predominant human α-2,6 sialic acid binding preference is essential for optimal transmission of this pandemic virus.
Journal ArticleDOI
Avian Influenza (H5N1) Viruses Isolated from Humans in Asia in 2004 Exhibit Increased Virulence in Mammals
Taronna R. Maines,Xui Hua Lu,Steven M. Erb,Lindsay Edwards,Jeannette Guarner,Patricia W. Greer,Doan C. Nguyen,Kristy J. Szretter,Li-Mei Chen,Pranee Thawatsupha,Malinee Chittaganpitch,Sunthareeya Waicharoen,Diep T. Nguyen,Tung Nguyen,Hanh T. Nguyen,Jae Hong Kim,Long T. Hoang,Chun Kang,Lien S. Phuong,Wilina Lim,Sherif R. Zaki,Ruben O. Donis,Nancy J. Cox,Jacqueline M. Katz,Terrence M. Tumpey +24 more
TL;DR: The results demonstrate the general equivalence of mouse and ferret models for assessment of the virulence of 2003 and 2004 H5N1 viruses, however, the apparent enhancement ofvirulence of these viruses in humans in 2004 was better reflected in the ferret.
Journal ArticleDOI
Evolution of H5N1 avian influenza viruses in Asia
Jean Thierry Aubin,Saliha Azebi,Amanda Balish,Jill Banks,Niranjan Bhat,Rick A. Bright,Ian Brown,Philippe Buchy,Ana Maria Burguiere,Hua Ian Chen,Peter K.C. Cheng,Nancy J. Cox,Alice Crosier,Aaron Curns,Frédérique Cuvelier,Guohua Deng,Julia Desheva,Stéphanie Desvaux,Nguyen Hong Diep,Ruben O. Donis,Ruben O. Donis,A. R. Douglas,Scott F. Dowell,Nguyen Tien Dung,Lindsay Edwards,Keiji Fukuda,Rebecca Garten,Elena A. Govorkova,Victoria Gregory,Alan W. Hampson,Nguyen Thi Hong Hanh,Scott A. Harper,A. Hay,Erich Hoffmann,Diane J. Hulse,Masaki Imai,Shigeyuki Itamura,Samadhan Jadhao,Patricia Jeannin,Chun Kang,Jackie Katz,Jae Hong Kim,Alexander Klimov,Yong Kuk Kwon,Chang-Won Lee,Phuong Song Lien,Yanbing Li,Wilina Lim,Yi Pu Lin,Stephen Lindstom,La Morris Loftin,Jan Mabry,Le Quynh Mai,Taronna R. Maines,Jean Claude Manuguerra,Masaji Mase,Yumi Matsuoka,Margaret McCarron,Marie-Jo Medina,Doan Nguyen,Ai Ninomiya,Masatsugu Obuchi,Takato Odagiri,Malik Peiris,Michael L. Perdue,Jean Marc Reynes,James Robertson,Claudine Rousseaux,Takehiko Saito,Somchai Sangkitporn,Michael W. Shaw,James Mark Simmerman,Marek J. Slomka,Catherine K. Smith,San Sorn,Erica Spackman,Klaus Stöhr,David L. Suarez,Haan Woo Sung,David E. Swayne,Maryse Tardy-Panit,Masato Tashiro,Pranee Thawatsupha,Terrence M. Tumpey,Timothy M. Uyeki,Phan Van Tu,Sylvie van der Werf,Sirenda Vong,Richard J. Webby,Robert G. Webster,John Wood,Xiyan Xu,Guan Yi,Wenging Zhang +93 more
TL;DR: Human infections were from a virus clade undergoing antigenic drift that showed resistance to adamantanes but sensitivity to neuraminidase inhibitors.
Journal ArticleDOI
Lack of transmission of H5N1 avian–human reassortant influenza viruses in a ferret model
Taronna R. Maines,Li-Mei Chen,Yumiko Matsuoka,Hualan Chen,Thomas Rowe,Juan Ortín,Ana Falcón,Nguyen Tran Hien,Le Quynh Mai,Endang R. Sedyaningsih,Syahrial Harun,Terrence M. Tumpey,Ruben O. Donis,Nancy J. Cox,Kanta Subbarao,Jacqueline M. Katz +15 more
TL;DR: It is suggested that H5N1 viruses may require further adaptation to acquire this essential pandemic trait, and the complexity of the genetic basis of influenza virus transmissibility is highlighted.