Diane M. Brooks

TL;DR: Air pollution causes neuroinflammation, an altered brain innate immune response, and accumulation of Aβ42 and α-synuclein starting in childhood, and carriers of the APOE 4 allele could have a higher risk of developing Alzheimer’s disease if they reside in a polluted environment.

TL;DR: The present work presents a groundbreaking, interdisciplinary methodology for addressing relationships between environmental pollution, structural brain alterations by MRI, and cognitive deficits/delays in healthy children.

TL;DR: In this article, the authors compared the olfactory function of individuals living under conditions of extreme air pollution to that of controls from a relatively clean environment and explore associations between olfaction scores, apolipoprotein E (APOE) status, and pollution exposure.

TL;DR: It is concluded that changes in specific inflammatory mediators such as LTE4 and PGI2 are related to arsenic-induced atherosclerosis, and amplified synthesis of reactive species such as peroxynitrite results in increased protein nitration in response to arsenic exposure.

TL;DR: The results suggest that arsenic toxicity is causative for mammalian spontaneous abortion by virtue of aberrant placental vasculogenesis and placental insufficiency.