Journal ArticleDOI
Bioactive iridium and rhodium complexes as therapeutic agents
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TLDR
A review of the recent strategies that have been utilized for the design and development of bioactive iridium and rhodium complexes can be found in this article, where the authors summarize the strategies used for the development and design of bio-active IR and RRS complexes.About:
This article is published in Coordination Chemistry Reviews.The article was published on 2013-06-01. It has received 251 citations till now. The article focuses on the topics: Ruthenium & Rhodium.read more
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Noble metals in medicine: Latest advances
Serenella Medici,Massimiliano Francesco Peana,Valeria Marina Nurchi,Joanna Izabela Lachowicz,Guido Crisponi,Maria Antonietta Zoroddu +5 more
TL;DR: A detailed account of the latest results of metal-based drugs and their potential uses in the cure of severe diseases is provided and the number of published studies in this field is huge.
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Organoiridium complexes: anticancer agents and catalysts.
Zhe Liu,Peter J. Sadler +1 more
TL;DR: In this paper, a review of recent developments in organoiridium complexes is presented, including the development of half-sandwich pseudo-octahedral pentamethylcyclopentadienyl IrIII complexes with diamine ligands.
Journal ArticleDOI
Recent development of biotin conjugation in biological imaging, sensing, and target delivery
TL;DR: New findings indicate that biotin orBiotin-conjugates could be favorably assimilated by tumor cells that over-express biotin-selective transporters.
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Update on metal N-heterocyclic carbene complexes as potential anti-tumor metallodrugs
Wukun Liu,Wukun Liu,Ronald Gust +2 more
TL;DR: In this article, the authors provide an update on the recent advances in this direction, which reflects new discoveries since the publication of their previous review, and discuss the anti-tumor properties along with the mechanisms of action for these complexes as well as possible structure-activity relationships.
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Recent Advances in Subcellular Targeted Cancer Therapy Based on Functional Materials.
TL;DR: Here, particular emphasis is placed on four kinds of therapies, including chemotherapy, gene therapy, photodynamic therapy (PDT), and hyperthermal therapy, which are the most widely used approaches for killing cancer cells by the specific destruction of subcellular organelles.
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Protein kinases--the major drug targets of the twenty-first century?
TL;DR: A personal view of some of the most important advances that have shaped this field of protein kinases, after G-protein-coupled receptors.
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The atomic structure of protein-protein recognition sites.
TL;DR: In this paper, the authors performed an analysis of the recognition sites seen in 75 protein-protein complexes of known three-dimensional structure: 24 protease-inhibitor, 19 antibody-antigen and 32 other complexes, including nine enzymeinhibitors and 11 that are involved in signal transduction.