Dimitar Kostadinov

TL;DR: Roles for the clustered protocadherins (Pcdhs) in dendritic self-avoidance and self/non-self discrimination are demonstrated, suggesting that homophilic Pcdhg interactions between sibling neurites (isoneuronal interactions) generate a repulsive signal that leads to self- avoidance.

TL;DR: A suite of electrophysiological tools comprising a miniaturized high-density probe, recoverable chronic implant fixtures, and algorithms for automatic post hoc motion correction are demonstrated, enabling an order-of-magnitude increase in the number of sites that can be recorded in small animals, such as mice, and the ability to record from them stably over long time scales.

TL;DR: Cerebellar climbing fibers carry predictive and feedback signals about reward, expanding the role of the cerebellar cortex in the creation and evaluation of predictions, and responses to predictable rewards are progressively suppressed during learning.

TL;DR: Self-avoidance, self/non-self discrimination, and synapse elimination are essential for proper function of a circuit that computes directional motion.

TL;DR: It is found that the transcriptional regulator Satb1 is selectively expressed by ooDSGCs, and directing formation of a morphologically and functionally specialized compartment within a complex dendritic arbor leads to branch-specific homophilic interactions with interneurons.