D
Dimitrios Tousoulis
Researcher at National and Kapodistrian University of Athens
Publications - 549
Citations - 10157
Dimitrios Tousoulis is an academic researcher from National and Kapodistrian University of Athens. The author has contributed to research in topics: Blood pressure & Population. The author has an hindex of 42, co-authored 535 publications receiving 7498 citations. Previous affiliations of Dimitrios Tousoulis include University of Bolton & Harokopio University.
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Journal ArticleDOI
Catheter-based renal denervation in patients with uncontrolled hypertension in the absence of antihypertensive medications (SPYRAL HTN-OFF MED): a randomised, sham-controlled, proof-of-concept trial
Raymond R. Townsend,Felix Mahfoud,Felix Mahfoud,David E. Kandzari,Kazuomi Kario,Stuart J. Pocock,Michael A. Weber,Sebastian Ewen,Konstantinos Tsioufis,Dimitrios Tousoulis,Andrew S.P. Sharp,A. Watkinson,Roland E. Schmieder,Axel Schmid,James W. Choi,Cara East,Anthony Walton,Ingrid Hopper,Debbie L. Cohen,Robert L. Wilensky,David P. Lee,Adrian Ma,Chandan Devireddy,Janice P. Lea,Philipp Lurz,Karl Fengler,Justin E. Davies,Neil Chapman,Sidney Cohen,Vanessa DeBruin,Martin Fahy,Denise E Jones,Martin T. Rothman,Michael Böhm,Jiro Aoki,Bryan Batson,George Dangas,Shukri David,David E. Kandzari,Manesh R. Patel,Kiritkumar Patel,Jasvindar Singh,Thomas Weber,Joachim Weil,Thomas Zeller,Khaled M. Ziada,Kengo Tanabe,Robert Wilkins,Johanna Contreras,Susan Steigerwalt,Denise Reedus,Satoshi Hoshide,Laura P. Svetkey,Anjani Rao,Angela L. Brown,Markus Suppan,Tolga Agdirlioglu,Elias Noory,Craig Chasen +58 more
TL;DR: Results from SPYRAL HTN-OFF MED provide biological proof of principle for the blood-pressure-lowering efficacy of renal denervation in the absence of antihypertensive medications.
Journal ArticleDOI
Effect of renal denervation on blood pressure in the presence of antihypertensive drugs: 6-month efficacy and safety results from the SPYRAL HTN-ON MED proof-of-concept randomised trial
David E. Kandzari,Michael Böhm,Felix Mahfoud,Felix Mahfoud,Raymond R. Townsend,Michael A. Weber,Stuart J. Pocock,Konstantinos Tsioufis,Dimitrios Tousoulis,James W. Choi,Cara East,Sandeep Brar,Sidney Cohen,Martin Fahy,Garrett Pilcher,Kazuomi Kario,Jiro Aoki,Bryan Batson,Debbie L. Cohen,George Dangas,Shukri David,Justin E. Davies,Chandan Devireddy,David E. Kandzari,David P. Lee,Philipp Lurz,Vasilios Papademetriou,Manesh R. Patel,Kiritkumar Patel,Roland E. Schmieder,Andrew S.P. Sharp,Jasvindar Singh,Antony Walton,Thomas Weber,Joachim Weil,Thomas Zeller,Khaled M. Ziada,Kengo Tanabe,Robert Wilkins,Robert L. Wilensky,Johanna Contreras,Susan Steigerwalt,Neil Chapman,Janice P. Lea,Denise Reedus,Satoshi Hoshide,Adrian Ma,Karl Fengler,Ping Li,Laura P. Svetkey,Anjani Rao,Axel Schmid,A. Watkinson,Angela L. Brown,Ingrid Hopper,Markus Suppan,Tolga Agdirlioglu,Elias Noory,Craig Chasen +58 more
TL;DR: Renal denervation in the main renal arteries and branches significantly reduced blood pressure compared with sham control with no major safety events.
Journal ArticleDOI
Effect of Colchicine vs Standard Care on Cardiac and Inflammatory Biomarkers and Clinical Outcomes in Patients Hospitalized With Coronavirus Disease 2019: The GRECCO-19 Randomized Clinical Trial.
Spyridon Deftereos,Georgios Giannopoulos,Dimitrios A. Vrachatis,Gerasimos Siasos,Sotiria G. Giotaki,Panagiotis Gargalianos,Simeon Metallidis,George Sianos,Stefanos Baltagiannis,Periklis Panagopoulos,Konstantinos Dolianitis,Efthalia Randou,Konstantinos N. Syrigos,Anastasia Kotanidou,Nikolaos Koulouris,Haralampos J. Milionis,Nikolaos V. Sipsas,Charalampos Gogos,George Tsoukalas,Christoforos Olympios,Eleftheria P Tsagalou,Ilias Migdalis,Styliani Gerakari,Christos Angelidis,Dimitrios Alexopoulos,Pericles Davlouros,George Hahalis,Ioannis Kanonidis,Demosthenes G. Katritsis,Theofilos M. Kolettis,Antonios S. Manolis,Lampros K. Michalis,Katerina K. Naka,Vlasios Pyrgakis,Konstantinos Toutouzas,Filippos Triposkiadis,Konstantinos Tsioufis,Emmanouil Vavouranakis,Luis Martínez-Dolz,Bernhard Reimers,Giulio G. Stefanini,Michael W. Cleman,John A. Goudevenos,Sotirios Tsiodras,Dimitrios Tousoulis,Efstathios K. Iliodromitis,Roxana Mehran,George Dangas,Christodoulos Stefanadis,Christodoulos Stefanadis +49 more
TL;DR: A role for colchicine in the treatment of patients with coronavirus disease 2019 is suggested, with results suggesting a smaller increase in dimerized plasma fragment D compared with patients in the control group.
Journal ArticleDOI
EU-wide cross-sectional observational study of lipid-modifying therapy use in secondary and primary care: the DA VINCI study
Kausik K. Ray,Bart Molemans,W. Marieke Schoonen,Periklis Giovas,Sarah Bray,Gaia Kiru,Jennifer Murphy,Maciej Banach,Maciej Banach,Maciej Banach,Stefano De Servi,Dan Gaita,Ioanna Gouni-Berthold,G. Kees Hovingh,Jacek Jerzy Jozwiak,J. Wouter Jukema,Róbert Gábor Kiss,Serge Kownator,Helle K. Iversen,Vincent Maher,Luis Masana,Alexander Parkhomenko,André Peeters,Piers Clifford,Katarina Raslova,Peter Siostrzonek,Stefano Romeo,Stefano Romeo,Stefano Romeo,Dimitrios Tousoulis,Charalambos Vlachopoulos,Michal Vrablík,Alberico L. Catapano,Neil R Poulter,DA Vinci study +34 more
TL;DR: In this article, the authors provide contemporary data on the implementation of European guideline recommendations for lipid-lowering therapies (LLTs) across different settings and populations and how this impacts low-density lipoprotein cholesterol (LDL-C) goal achievement.
Journal ArticleDOI
Adiponectin as a link between type 2 diabetes and vascular NADPH oxidase activity in the human arterial wall: the regulatory role of perivascular adipose tissue.
Alexios S. Antonopoulos,Marios Margaritis,Patricia Coutinho,Cheerag Shirodaria,Costas Psarros,L Herdman,Fabio Sanna,R De Silva,Mario Petrou,Rana Sayeed,George Krasopoulos,Regent Lee,Janet E. Digby,Svetlana Reilly,Constantinos Bakogiannis,Dimitrios Tousoulis,Benedikt M. Kessler,Barbara Casadei,Keith M. Channon,Charalambos Antoniades +19 more
TL;DR: It is demonstrated for the first time in humans that reduced adiponectin levels in individuals with type 2 diabetes stimulates vascular NADPH oxidase, while PVAT “senses” the increased NAD PH oxidase activity in the underlying vessel and responds by upregulating adiponECTin gene expression.