D
Dipak K. Das
Researcher at University of Connecticut
Publications - 329
Citations - 18415
Dipak K. Das is an academic researcher from University of Connecticut. The author has contributed to research in topics: Ischemia & Resveratrol. The author has an hindex of 75, co-authored 327 publications receiving 17708 citations. Previous affiliations of Dipak K. Das include Jawaharlal Nehru University & Baystate Medical Center.
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Journal ArticleDOI
Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention
Debasis Bagchi,Manashi Bagchi,Sidney J. Stohs,Dipak K. Das,Sidhartha D. Ray,Charles A. Kuszynski,Shantaram S. Joshi,Harry G Pruess +7 more
TL;DR: It is demonstrated that GSPE is highly bioavailable and provides significantly greater protection against free radicals and free radical-induced lipid peroxidation and DNA damage than vitamins C, E and beta-carotene.
Journal ArticleDOI
What Is New for an Old Molecule? Systematic Review and Recommendations on the Use of Resveratrol
Ole Vang,Nihal Ahmad,Clifton A. Baile,Joseph A. Baur,Karen Brown,Anna Csiszar,Dipak K. Das,Dominique Delmas,Carmem Gottfried,Hung Yun Lin,Qing-Yong Ma,Partha Mukhopadhyay,Namasivayam Nalini,John M. Pezzuto,Tristan Richard,Yogeshwer Shukla,Young-Joon Surh,Thomas Szekeres,Tomasz Szkudelski,Thomas Walle,Joseph M. Wu +20 more
TL;DR: The published evidence is not sufficiently strong to justify a recommendation for the administration of resveratrol to humans, beyond the dose which can be obtained from dietary sources, and animal data are promising in prevention of various cancer types, coronary heart diseases and diabetes which strongly indicate the need for human clinical trials.
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Molecular mechanisms of cardioprotection by a novel grape seed proanthocyanidin extract.
Debasis Bagchi,Chandan K. Sen,Sidhartha D. Ray,Dipak K. Das,Manashi Bagchi,Harry G. Preuss,Joe A. Vinson +6 more
TL;DR: It is demonstrated that IH636 grape seed proanthocyanidin extract (GSPE) provides superior antioxidant efficacy as compared to Vitamins C, E and beta-carotene and may serve as a potential therapeutic tool in promoting cardiovascular health via a number of novel mechanisms.
Journal ArticleDOI
Anti-inflammatory responses of resveratrol.
Samarjit Das,Dipak K. Das +1 more
TL;DR: Evidence is provided that resveratrol exhibits potent anti-inflammatory activity and the mechanisms discussed address foremost mechanisms for the anti- inflammatory activity which, in turn, is responsible for cardioprotection.
Journal ArticleDOI
The red wine antioxidant resveratrol protects isolated rat hearts from ischemia reperfusion injury.
Partha S. Ray,Gautam Maulik,Gerald A. Cordis,Alberto A.E. Bertelli,Aldo Bertelli,Dipak K. Das +5 more
TL;DR: The results of this study demonstrate that resveratrol possesses cardioprotective effects which may be attributed to its peroxyl radical scavenging activity and suggest a probable mechanism involved in the protective ability of RVT.