Dmitry Meleshko

TL;DR: MetaSPAdes as mentioned in this paper addresses various challenges of metagenomic assembly by capitalizing on computational ideas that proved to be useful in assemblies of single cells and highly polymorphic diploid genomes.

TL;DR: Protocols for five different assembly pipelines that comprise the SPAdes package and that are used for assembly of metagenomes and transcriptomes as well as assembly of putative plasmids and biosynthetic gene clusters from whole‐genome sequencing and metagenomic datasets are presented.

TL;DR: The utility of the living data resource and cross-cohort comparison is demonstrated to confirm existing associations between the microbiome and psychiatric illness and to reveal the extent of microbiome change within one individual during surgery, providing a paradigm for open microbiome research and education.

TL;DR: It is shown that a citizen-science, self-selected cohort shipping samples through the mail at room temperature recaptures many known microbiome results from clinically collected cohorts and reveals new ones, and that the extent of microbiome change after events such as surgery can exceed differences between distinct environmental biomes.

TL;DR: A free and comprehensive database of nucleic acid sequences, characterised novel viruses related to coronaviruses and to hepatitis δ virus, respectively and explored their environmental reservoirs.