James Gaffney

TL;DR: The utility of the living data resource and cross-cohort comparison is demonstrated to confirm existing associations between the microbiome and psychiatric illness and to reveal the extent of microbiome change within one individual during surgery, providing a paradigm for open microbiome research and education.

TL;DR: The findings indicate that mammalian gut microbiome plasticity in response to dietary shifts over both the lifespan of an individual host and the evolutionary history of a given host species is constrained by host physiological evolution, and the gut microbiome cannot be considered separately from host physiology when describing host nutritional strategies and the emergence of host dietary niches.

TL;DR: It is shown that a citizen-science, self-selected cohort shipping samples through the mail at room temperature recaptures many known microbiome results from clinically collected cohorts and reveals new ones, and that the extent of microbiome change after events such as surgery can exceed differences between distinct environmental biomes.

TL;DR: An extraction pipeline is identified that dramatically reduces sample processing time without sacrificing bacterial taxonomic or abundance information in the shortest amount of time.

TL;DR: Fecal samples from two species of howler monkey are utilized to investigate factors influencing the gut microbiota at three scales: taxonomic (host species), ecosystemic (forest type), and local (habitat disturbance/season).