D
Dong Yin
Researcher at University of California, Los Angeles
Publications - 49
Citations - 3939
Dong Yin is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Cell growth & Cell culture. The author has an hindex of 33, co-authored 41 publications receiving 3658 citations. Previous affiliations of Dong Yin include Memorial Hospital of South Bend & Cedars-Sinai Medical Center.
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Journal ArticleDOI
Genomic and molecular characterization of esophageal squamous cell carcinoma
De-Chen Lin,De-Chen Lin,Jia-Jie Hao,Yasunobu Nagata,Liang Xu,Li Shang,Xuan Meng,Yusuke Sato,Yusuke Okuno,Ana Maria Varela,Ling-Wen Ding,Manoj Garg,Li-Zhen Liu,Henry Yang,Dong Yin,Zhi-Zhou Shi,Yan-Yi Jiang,Wen-Yue Gu,Ting Gong,Yu Zhang,Xin Xu,Ori Kalid,Sharon Shacham,Seishi Ogawa,Ming-Rong Wang,H. Phillip Koeffler,H. Phillip Koeffler +26 more
TL;DR: The whole-exome or targeted deep sequencing of 139 paired ESCC cases and analysis of somatic copy number variations (SCNV) of over 180 ESCCs provide an important molecular foundation for understanding esophageal tumors and developing therapeutic targets.
Journal ArticleDOI
Proteasome inhibitor PS-341 causes cell growth arrest and apoptosis in human glioblastoma multiforme (GBM).
Dong Yin,Hong Zhou,Takashi Kumagai,Gentao Liu,John M. Ong,Keith L. Black,H. Phillip Koeffler +6 more
TL;DR: Examining its antiproliferation, proapoptotic effects using three human glioblastoma multiforme cell lines and five primary GBM explants suggests that PS-341 may be an effective therapy for patients with gliomas.
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Cucurbitacin B Induces Apoptosis by Inhibition of the JAK/STAT Pathway and Potentiates Antiproliferative Effects of Gemcitabine on Pancreatic Cancer Cells
Nils H. Thoennissen,Gabriela B. Iwanski,Ngan B. Doan,Ryoko Okamoto,Patricia Lin,Sam Abbassi,Jee Hoon Song,Dong Yin,Melvin Toh,Wei Dong Xie,Jonathan W. Said,H. Phillip Koeffler +11 more
TL;DR: It is shown for the first time that cucurbitacin B has profound in vitro and in vivo antiproliferative effects against human pancreatic cancer cells, and the compound may potentate the antiprolifierative effect of the chemotherapeutic agent gemcitabine.
Journal ArticleDOI
Levels of Expression of CYR61 and CTGF Are Prognostic for Tumor Progression and Survival of Individuals with Gliomas
Dong Xie,Dong Yin,He-Jing Wang,Gentao Liu,Robert Elashoff,Keith L. Black,H. Phillip Koeffler +6 more
TL;DR: The results suggest that CYR61 and CTGF may play a role in the progression of gliomas; their levels at diagnosis may have prognostic significance; and these proteins might serve as valuable targets for therapeutic intervention.
Journal ArticleDOI
Short- and Long-term Outcomes after Laparoscopic and Open Hepatectomy for Hepatocellular Carcinoma: A Global Systematic Review and Meta-analysis
TL;DR: In patients with solitary left lateral lobe/right peripheral subcapsular tumors treated with minor resection, this meta-analysis demonstrated that compared to OH, LH may have short-term advantages in terms of blood loss and postoperative morbidity for HCC.