D
Doug Hyatt
Researcher at Oak Ridge National Laboratory
Publications - 13
Citations - 8076
Doug Hyatt is an academic researcher from Oak Ridge National Laboratory. The author has contributed to research in topics: Genome & Genome project. The author has an hindex of 8, co-authored 13 publications receiving 5930 citations. Previous affiliations of Doug Hyatt include University of Tennessee.
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Journal ArticleDOI
Prodigal: prokaryotic gene recognition and translation initiation site identification
Doug Hyatt,Doug Hyatt,Gwo Liang Chen,Philip F. LoCascio,Miriam Land,Frank W. Larimer,Frank W. Larimer,Loren Hauser +7 more
TL;DR: This work developed a new gene prediction algorithm called Prodigal (PROkaryotic DYnamic programming Gene-finding ALgorithm), which achieved good results compared to existing methods, and it is believed it will be a valuable asset to automated microbial annotation pipelines.
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Gene and translation initiation site prediction in metagenomic sequences
TL;DR: MetaProdigal is presented, a metagenomic version of the gene prediction program Prodigal that can identify genes in short, anonymous coding sequences with a high degree of accuracy and can identify sequences that use alternate genetic codes and confidence values for each gene call.
Journal ArticleDOI
Enigmatic, ultrasmall, uncultivated Archaea
Brett J. Baker,Luis R. Comolli,Gregory J. Dick,Loren Hauser,Doug Hyatt,Brian D. Dill,Miriam Land,Nathan C Verberkmoes,Robert L. Hettich,Jillian F. Banfield,Jillian F. Banfield +10 more
TL;DR: This article reconstructed composite, near-complete approximately 1-Mb genomes for three lineages, referred to as ARMAN (archaeal Richmond Mine acidophilic nanoorganisms), from environmental samples and a biofilm filtrate.
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Quantitative Tracking of Isotope Flows in Proteomes of Microbial Communities
Chongle Pan,Curt R. Fischer,Doug Hyatt,Benjamin P. Bowen,Robert L. Hettich,Jillian F. Banfield +5 more
TL;DR: In this paper, a stable isotope probing (SIP) method was used to track nutrient flows in microbial communities, but existing protein-based SIP methods capable of quantifying the degree of label incorporation into peptides and proteins have been demonstrated only by targeting usually less than 100 proteins per sample.
Journal ArticleDOI
Quality scores for 32,000 genomes
Miriam Land,Doug Hyatt,Doug Hyatt,Se-Ran Jun,Guruprasad Kora,Loren Hauser,Loren Hauser,Oksana Lukjancenko,David W. Ussery,David W. Ussery,David W. Ussery +10 more
TL;DR: The score can be used to set thresholds for screening data when analyzing “all published genomes” and reference data is either not available or not applicable and the scores highlighted organisms for which commonly used tools do not perform well.