E. van de Vosse

TL;DR: The mutation analysis revealed a high preponderance of mutations involving or creating cysteine residues, pointing to sites important for the tertiary folding and/or protein function, and highlights several amino acids which may be involved in XLRS1-specific protein-protein interactions.

TL;DR: It is suggested that this polymorphism in PARK2/PACRG plays a small but significant role in susceptibility to the intracellular pathogens S. typhi and S. paratyphi A, intrACEllular pathogens that upon infection of humans share with mycobacteria aspects of the hosts’ immune response.

TL;DR: While rdgC is expressed in the visual system of the fly, as well as in the mushroom bodies of the central brain, it is found that Ppef is highly expressed in sensory neurons of the dorsal root ganglia and neural crest-derived cranial ganglia, which suggests a role for serine-threonine phosphatases in mammalian development.

TL;DR: The data suggest that insight into absolute DNA copy numbers for loci exhibiting CNV is required to determine their potential contribution to normal phenotypic variation and, in addition, disease susceptibility.

TL;DR: The observation that plasma granulysin levels and cellular IFN-gamma production correlate with curative host responses in pulmonary tuberculosis points to a potentially important role ofgranulysin, next to IFN -gamma, in host defence against M. tuberculosis.