E
Eberhardt Herdtweck
Researcher at Technische Universität München
Publications - 332
Citations - 11434
Eberhardt Herdtweck is an academic researcher from Technische Universität München. The author has contributed to research in topics: Catalysis & Carbene. The author has an hindex of 56, co-authored 332 publications receiving 10785 citations. Previous affiliations of Eberhardt Herdtweck include Jordan University of Science and Technology & Ludwig Maximilian University of Munich.
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A Universal Isocyanide for Diverse Heterocycle Syntheses
TL;DR: Three different heterocyclic scaffolds easily accessible from isocyanoacetaldehyde dimethylacetal 1 by multicomponent reaction (MCR) are described and the synthesis, 3D structures, and other physicochemical properties are discussed.
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Bis(π-pentamethylcyclopentadienyl)(2-methyliden) titanacyclobutan: Selektive insertion von isonitrilen und diphenylketen—Bildung fünf- und sechsgliedriger metallacyclen
TL;DR: In this article, the reaction of isonitriles or diphenylketene with the titanacyclobutane derivative Cp2★ TiC(CH2)CH2CH2 (2) (Cp★ = [C5(CH3)5]) at room temperature afforded the five-and six-membered metallacycles Cp 2★TiC( ǫC(ǫ)CH 2 )CH2 CH2C(PH2)O (11), respectively, whose structures have been characterized by
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Tetrazole and triazole carbene complexes of group 6 metal carbonyls
TL;DR: In this article, the relative stability of bis(NHC)tetracarbonyl complexes of group 6 metals was studied by using triazolin-and tetrazolinylidene ligands.
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Receptor‐Bound Conformation of Cilengitide Better Represented by Its Solution‐State Structure than the Solid‐State Structure
Udaya Kiran Marelli,Andreas O. Frank,Andreas O. Frank,Bernhard Wahl,Valeria La Pietra,Ettore Novellino,Luciana Marinelli,Eberhardt Herdtweck,Michael Groll,Horst Kessler,Horst Kessler +10 more
TL;DR: Molecular modeling studies of the various ligand structures docked to the αvβ3 integrin revealed that utilization of the solid-state conformation of Cilengitide leads-unlike the solution-based structures-to a mismatch of the ligand-receptor interactions compared with the experimentally determined structure of the protein-ligand complex.
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A Versatile Synthesis of 6-Oxo-1,4,5,6-tetrahydro-pyrazine-2-carboxylic Acid Methyl Esters via MCR Chemistry
TL;DR: In this paper, a three-component, one-pot condensation yielding 6-oxo-1,4,5,6-tetrahydro-pyrazine-2-carboxylic acid methyl esters from aldehydes, amines and 3-dimethylamino-2isocyano-acrylic acid methyl enters is described.