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Edgar L. Milford
Researcher at Brigham and Women's Hospital
Publications - 225
Citations - 18072
Edgar L. Milford is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Transplantation & Antigen. The author has an hindex of 54, co-authored 223 publications receiving 16954 citations. Previous affiliations of Edgar L. Milford include Cornell University & University of Utah.
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Journal ArticleDOI
Fatal autoimmunity in mice reconstituted with human hematopoietic stem cells encoding defective FOXP3
Jeremy A. Goettel,Jeremy A. Goettel,Subhabrata Biswas,Willem S. Lexmond,Willem S. Lexmond,Ada Yeste,Ada Yeste,Laura Passerini,Bonny Patel,Bonny Patel,Siyoung Yang,Jiusong Sun,Jodie Ouahed,Jodie Ouahed,Dror S. Shouval,Dror S. Shouval,Katelyn McCann,Bruce H. Horwitz,Bruce H. Horwitz,Diane Mathis,Edgar L. Milford,Edgar L. Milford,Luigi D. Notarangelo,Luigi D. Notarangelo,Maria Grazia Roncarolo,Edda Fiebiger,Edda Fiebiger,Wayne A. Marasco,Rosa Bacchetta,Francisco J. Quintana,Francisco J. Quintana,Sung-Yun Pai,Sung-Yun Pai,Christoph Klein,Aleixo M. Muise,Scott B. Snapper,Scott B. Snapper,Scott B. Snapper +37 more
TL;DR: A humanized mouse model that lacks murine major histocompatibility complex class II and instead expresses human leukocyte antigen DR1 (HLA-DR1) permits in vivo evaluation of immune responses associated with genetically altered HSCs, including primary immunodeficiencies, and should facilitate the study of human immune pathobiology and the development of targeted therapeutics.
Journal Article
Soluble class I HLA antigens in patients with rheumatoid arthritis and their families.
I. Adamashvili,John C. McDonald,Patricia A. Fraser,Edgar L. Milford,Thomas Pressly,Frank B. Gelder +5 more
TL;DR: SHLAI may play a role in the pathophysiology of RA, and there is an association between either augmented release or production of sHLAI and specific HLA allotypes.
Journal Article
Computer program to predict likelihood of finding and HLA-matched donor: methodology, validation, and application.
TL;DR: A mathematical algorithm and computer program to facilitate the search for a suitable donor by donor race and phenotype and the results of the validation study show that the prediction is highly accurate at the level of broad antigens.
Journal ArticleDOI
Association of Donor and Recipient Telomere Length with Clinical Outcomes following Lung Transplantation.
Andrew M. Courtwright,Sabrina Fried,Julian A. Villalba,Anna Moniodis,Indira Guleria,Isabelle G. Wood,Edgar L. Milford,H. Mallidi,Gary M. Hunninghake,Benjamin A. Raby,Suneet Agarwal,Philip C. Camp,Ivan O. Rosas,Hilary J. Goldberg,Souheil El-Chemaly +14 more
TL;DR: Neither long donor lymphocyte telomeres nor short recipient lung tissue telomere lengths were associated with adjusted survival after lung transplantation in this small cohort of patients.
Journal ArticleDOI
Managing anemia in dialysis patients: hemoglobin cycling and overshoot
TL;DR: A 67-year-old African American female with end-stage renal disease secondary to renal artery stenosis and ischemic nephropathy presents with increased somnolence of 1-day duration and is drowsy on admission.