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Peihua Niu
Researcher at Chinese Center for Disease Control and Prevention
Publications - 48
Citations - 37230
Peihua Niu is an academic researcher from Chinese Center for Disease Control and Prevention. The author has contributed to research in topics: Medicine & Coronavirus. The author has an hindex of 16, co-authored 39 publications receiving 27101 citations. Previous affiliations of Peihua Niu include National Health and Family Planning Commission.
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Journal ArticleDOI
A Novel Coronavirus from Patients with Pneumonia in China, 2019.
Na Zhu,Dingyu Zhang,Wenling Wang,Xingwang Li,Bo Yang,Jingdong Song,Xiang Zhao,Baoying Huang,Weifeng Shi,Roujian Lu,Peihua Niu,Faxian Zhan,Xuejun Ma,Dayan Wang,Wenbo Xu,Wenbo Xu,Guizhen Wu,George F. Gao,Wenjie Tan +18 more
TL;DR: Human airway epithelial cells were used to isolate a novel coronavirus, named 2019-nCoV, which formed a clade within the subgenus sarbecovirus, Orthocoronavirinae subfamily, which is the seventh member of the family of coronaviruses that infect humans.
Journal ArticleDOI
Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding.
Roujian Lu,Xiang Zhao,Juan Li,Peihua Niu,Bo Yang,Honglong Wu,Wenling Wang,Hao Song,Baoying Huang,Na Zhu,Yuhai Bi,Xuejun Ma,Faxian Zhan,Liang Wang,Tao Hu,Hong Zhou,Zhenhong Hu,Weimin Zhou,Li Zhao,Jing Chen,Yao Meng,Ji Wang,Yang Lin,Jianying Yuan,Zhihao Xie,Jinmin Ma,William J. Liu,Dayan Wang,Wenbo Xu,Edward C. Holmes,George F. Gao,George F. Gao,Guizhen Wu,Weijun Chen,Weifeng Shi,Wenjie Tan,Wenjie Tan +36 more
TL;DR: The phylogenetic analysis suggests that bats might be the original host of this virus, an animal sold at the seafood market in Wuhan might represent an intermediate host facilitating the emergence of the virus in humans.
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In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
Xueting Yao,Fei Ye,Miao Zhang,Cheng Cui,Baoying Huang,Peihua Niu,Xu Liu,Li Zhao,Erdan Dong,Chunli Song,Siyan Zhan,Roujian Lu,Haiyan Li,Wenjie Tan,Dongyang Liu +14 more
TL;DR: It is proposed that the immunomodulatory effect of hydroxychloroquine also may be useful in controlling the cytokine storm that occurs late-phase in critically ill SARS-CoV-2 infected patients.
Journal ArticleDOI
Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China.
Aiping Wu,Yousong Peng,Baoying Huang,Xiao Ding,Xianyue Wang,Peihua Niu,Jing Meng,Zhaozhong Zhu,Zheng Zhang,Jiangyuan Wang,Jie Sheng,Lijun Quan,Zanxian Xia,Wenjie Tan,Genhong Cheng,Taijiao Jiang +15 more
TL;DR: An in-depth annotation of the newly discovered coronavirus (2019-nCoV) genome has revealed differences between 2019-n coV and severe acute respiratory syndrome (SARS) or SARS-like coronaviruses.
Journal ArticleDOI
Development of an Inactivated Vaccine Candidate, BBIBP-CorV, with Potent Protection against SARS-CoV-2.
Hui Wang,Yuntao Zhang,Baoying Huang,Wei Deng,Yaru Quan,Wenling Wang,Wenbo Xu,Yuxiu Zhao,Na Li,Jin Zhang,Hongyang Liang,Linlin Bao,Yanfeng Xu,Ling Ding,Weimin Zhou,Hong Gao,Jiangning Liu,Peihua Niu,Li Zhao,Wei Zhen,Hui Fu,Yu Shouzhi,Zhang Zhengli,Guangxue Xu,Changgui Li,Zhiyong Lou,Miao Xu,Chuan Qin,Guizhen Wu,George F. Gao,Wenjie Tan,Xiaoming Yang +31 more
TL;DR: Two-dose immunizations using 2 μg/dose of BBIBP-CorV provided highly efficient protection against SARS-CoV-2 intratracheal challenge in rhesus macaques, without detectable antibody-dependent enhancement of infection.