E
Edward Korzus
Researcher at University of California, Riverside
Publications - 27
Citations - 4194
Edward Korzus is an academic researcher from University of California, Riverside. The author has contributed to research in topics: CREB-binding protein & Prefrontal cortex. The author has an hindex of 19, co-authored 27 publications receiving 4044 citations. Previous affiliations of Edward Korzus include Scripps Research Institute & Max Planck Society.
Papers
More filters
Journal ArticleDOI
The serpin superfamily of proteinase inhibitors: structure, function, and regulation.
Journal ArticleDOI
CBP Histone Acetyltransferase Activity Is a Critical Component of Memory Consolidation
TL;DR: The behavioral phenotype is due to an acute requirement for CBP HAT activity in the adult as it is rescued by both suppression of transgene expression or by administration of the histone deacetylase inhibitor Trichostatin A in adult animals.
Journal ArticleDOI
Transcription Factor-Specific Requirements for Coactivators and Their Acetyltransferase Functions
Edward Korzus,Joseph Torchia,David W. Rose,Lan Xu,Riki Kurokawa,Eileen M. McInerney,Tina-Marie Mullen,Christopher K. Glass,Michael G. Rosenfeld +8 more
TL;DR: Different classes of mammalian transcription factors functionally require distinct components of the coactivator complex, including CREB-binding protein (CBP/p300), nuclear receptor coactivators (NCoAs), and p300/CBP-associated factor (p/CAF).
Journal ArticleDOI
Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300
Andrew E. Horvai,Lan Xu,Edward Korzus,Gyan Brard,Daniel Kalafus,Tina-Marie Mullen,David W. Rose,Michael G. Rosenfeld,Christopher K. Glass +8 more
TL;DR: CBP and p300 integrate both positive and negative effects of IFN-gamma on gene expression by serving as essential coactivators of STAT1 alpha, modulating gene-specific responses to simultaneous activation of two or more signal transduction pathways.
Journal ArticleDOI
Signal-specific co-activator domain requirements for Pit-1 activation
Lan Xu,Robert M. Lavinsky,Jeremy S. Dasen,Sarah E. Flynn,Eileen M. McInerney,Tina-Marie Mullen,Thorsten Heinzel,Daniel P. Szeto,Edward Korzus,Riki Kurokawa,Aneel K. Aggarwal,David W. Rose,Christopher K. Glass,Michael G. Rosenfeld +13 more
TL;DR: There is a switch in specific requirements for histone acetyltransferase functions of CBP, or p/CAF are required for Pit-1 function that is stimulated by cyclic AMP or growth factors, respectively, showing the effects of different signal-transduction pathways on specific DNA-bound transcription factors.