E
Eileen White
Researcher at Rutgers University
Publications - 241
Citations - 51179
Eileen White is an academic researcher from Rutgers University. The author has contributed to research in topics: Autophagy & Programmed cell death. The author has an hindex of 95, co-authored 226 publications receiving 44992 citations. Previous affiliations of Eileen White include University of Tokyo & University of Medicine and Dentistry of New Jersey.
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An autophagy-dependent anticancer immune response determines the efficacy of melanoma chemotherapy
Mickaël Michaud,Xiaoqi Xie,José Manuel Bravo-San Pedro,Laurence Zitvogel,Eileen White,Guido Kroemer +5 more
TL;DR: It appears that the success of chemotherapy against “spontaneous,” genetically induced cancers is governed by the same rules as those applicable to transplantable tumors.
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Apoptosis-Inducing Galactolipids from a Cultured Marine Diatom, Phaeodactylum tricornutum
Eric H. Andrianasolo,Liti Haramaty,Assaf Vardi,Eileen White,Richard A. Lutz,Paul G. Falkowski +5 more
TL;DR: The first report of apoptosis induction by galactolipids is reported, using genetically engineered mammalian cell lines with differential, defined capacities for apoptosis.
Journal Article
Interleukin 1 beta converting enzyme-like proteases are essential for p53-mediated transcriptionally dependent apoptosis.
TL;DR: Results indicate that all apoptotic pathways downstream of p53-mediated transcription converge upon the activation of ICE-like proteases.
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Deleted in Breast Cancer 1, a Novel Androgen Receptor (AR) Coactivator That Promotes AR DNA-binding Activity
Junjiang Fu,Junjiang Fu,Jun Jiang,Jiwen Li,Shanshan Wang,Guang Shi,Qin Feng,Eileen White,Jun Qin,Jiemin Wong +9 more
TL;DR: The identification of a novel AR coactivator, deleted in breast cancer 1 (DBC1), through a biochemical approach is reported, which interacts with AR in a ligand-stimulated manner and facilitates AR transcriptional activation in transfected cells as well as in Xenopus oocytes.
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Effect of dual inhibition of apoptosis and autophagy in prostate cancer.
Ahamed Saleem,Dmitri Dvorzhinski,Urmila Santanam,Robin Mathew,Kevin Bray,M. N. Stein,Eileen White,Eileen White,Robert S. DiPaola +8 more
TL;DR: Targeting multiple anti‐apoptotic proteins is now possible with the small molecule BH3 domain mimetics such as ABT‐737, and it is hypothesized that hydroxychloroquine (HCQ), an anti‐malarial drug that inhibits autophagy, will increase cytotoxicity of ABT-737.