Eileen White

TL;DR: It is reported that knock-out of eEF2K protects mice from a lethal dose of whole-body ionizing radiation at 8 Gy by reducing apoptosis levels in both bone marrow and gastrointestinal tracts and suggests that protective versus pro-apoptotic roles of e EF2K depend on the type of cells: eEF1K is protective in highly proliferative cells, which are more susceptible to mitotic catastrophe.

TL;DR: Results indicate that the enhancement of bleomycin induced DNA damage by trifluoperazine is mediated, at least in part, through the induction of apoptosis.

TL;DR: The current status of autophagy research with a particular focus on human diseases is summarized in this paper, where the authors present a review of the current state of the art in this area.

TL;DR: This finding is the first report of chemical compounds that induce apoptosis from the cultured deep-sea marine organism, hydrothermal vent bacterium, Thermovibrio ammonificans.

TL;DR: Results indicate that the previously isolated diterpenes affects cell in a manner similar to that of HSP90 and HDAC inhibitors and in a way opposite of PI3 kinase/mTOR inhibitors.