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Eilidh Carrington
Researcher at University of Basel
Publications - 4
Citations - 219
Eilidh Carrington is an academic researcher from University of Basel. The author has contributed to research in topics: Plasmodium falciparum & Heterochromatin protein 1. The author has an hindex of 2, co-authored 4 publications receiving 120 citations. Previous affiliations of Eilidh Carrington include Swiss Tropical and Public Health Institute.
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Journal ArticleDOI
GDV1 induces sexual commitment of malaria parasites by antagonizing HP1-dependent gene silencing
Michael Filarsky,Michael Filarsky,Sabine Anne-Kristin Fraschka,Igor Niederwieser,Igor Niederwieser,Nicolas M. B. Brancucci,Nicolas M. B. Brancucci,Eilidh Carrington,Eilidh Carrington,Elvira Carrio,Elvira Carrio,Suzette Moes,Paul Jenoe,Richárd Bártfai,Till S. Voss,Till S. Voss +15 more
TL;DR: This study identified Plasmodium falciparum gametocyte development 1 (GDV1) as an upstream activator of sexual commitment and found that GDV1 targeted heterochromatin and triggered HP1 eviction, thus derepressing ap2-g.
Journal ArticleDOI
CRISPR/Cas9-engineered inducible gametocyte producer lines as a valuable tool for Plasmodium falciparum malaria transmission research.
Sylwia D. Boltryk,Sylwia D. Boltryk,Armin Passecker,Armin Passecker,Arne Alder,Arne Alder,Eilidh Carrington,Eilidh Carrington,Marga van de Vegte-Bolmer,Geert-Jan van Gemert,Alex van der Starre,Hans-Peter Beck,Hans-Peter Beck,Robert W. Sauerwein,Taco W. A. Kooij,Nicolas M. B. Brancucci,Nicolas M. B. Brancucci,Nicholas I Proellochs,Tim-Wolf Gilberger,Tim-Wolf Gilberger,Till S. Voss,Till S. Voss +21 more
TL;DR: In this paper, P. falciparum NF54 inducible gametocyte producer (iGP) lines for the routine mass production of synchronous gametocytes via conditional overexpression of the sexual commitment factor GDV1.
Journal ArticleDOI
The ApiAP2 factor PfAP2-HC is an integral component of heterochromatin in the malaria parasite Plasmodium falciparum
Eilidh Carrington,Eilidh Carrington,Roel H. M. Cooijmans,Dominique Keller,Dominique Keller,Christa Geeke Toenhake,Richárd Bártfai,Till S. Voss,Till S. Voss +8 more
TL;DR: In this article, an ApiAP2-HC was found to be a core component of heterochromatin in malaria parasites and identified unexpected properties and substantial functional divergence among the members of the Api-AP2 family of regulatory proteins.
Posted ContentDOI
The ApiAP2 factor PfAP2-HC is an integral component of heterochromatin in the malaria parasite Plasmodium falciparum
Eilidh Carrington,Eilidh Carrington,Roel H. M. Cooijmans,Dominique Keller,Dominique Keller,Christa Geeke Toenhake,Richárd Bártfai,Till S. Voss,Till S. Voss +8 more
TL;DR: The findings reveal that PfAP2-HC constitutes a core component of heterochromatin in malaria parasites and furthermore identify unexpected properties of ApiAP2 factors and suggest substantial functional divergence among the members of this important family of regulatory proteins.