Einar Bjornsson

TL;DR: Drug-Induced Liver Injury The liver has a range of responses to drug-induced injury, with a number of phenotypes, and idiosyncratic reactions may occur as a consequence of both direct and indirect drug exposure.

TL;DR: Drug-induced liver injury (DILI) is an adverse reaction to drugs or other xenobiotics that occurs either as a predictable event when an individual is exposed to toxic doses of some compounds or as an unpredictable event with many drugs in common use as discussed by the authors.

TL;DR: Current challenges in the diagnosis and management of HDS‐induced liver injury were the focus of a 2‐day research symposium sponsored by the American Association for the Study of Liver Disease and the National Institutes of Health.

TL;DR: It is found that FUT2 secretor status and genotype defined by rs601338 significantly influence biliary microbial community composition in PSC patients, and multiple new PSC risk loci are identified by extended analysis of a GWAS.

TL;DR: In this article, the authors classified drugs into categories based on the number of published reports of convincingly documented, clinically apparent, idiosyncratic liver injury, using the Roussel Uclaf Causality Assessment Method.