E
Eleni Karakike
Researcher at National and Kapodistrian University of Athens
Publications - 16
Citations - 542
Eleni Karakike is an academic researcher from National and Kapodistrian University of Athens. The author has contributed to research in topics: Sepsis & SuPAR. The author has an hindex of 6, co-authored 13 publications receiving 239 citations.
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Journal ArticleDOI
Macrophage Activation-Like Syndrome: A Distinct Entity Leading to Early Death in Sepsis.
TL;DR: Patients meeting the Sepsis-3 criteria and who had positive HSscore or co-presence of HBD and disseminated intravascular coagulation (DIC) were classified as patients with macrophage activation-like syndrome (MALS), and ferritin was proposed as a diagnostic and surrogate biomarker.
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An open label trial of anakinra to prevent respiratory failure in COVID-19.
Evdoxia Kyriazopoulou,Periklis Panagopoulos,Symeon Metallidis,George N. Dalekos,Garyphallia Poulakou,Nikolaos K. Gatselis,Eleni Karakike,Maria Saridaki,Georgia Loli,Aggelos Stefos,Danai Prasianaki,Sarah P. Georgiadou,Olga Tsachouridou,Vasileios Petrakis,Konstantinos Tsiakos,Maria Kosmidou,Vassiliki Lygoura,Maria Dareioti,Haralampos J. Milionis,Ilias Papanikolaou,Karolina Akinosoglou,Dimitra-Melia Myrodia,Areti Gravvani,Aliki Stamou,Theologia Gkavogianni,Konstantina Katrini,Theodoros Marantos,Ioannis P Trontzas,Konstantinos N. Syrigos,L. Chatzis,Stamatios Chatzis,Nikolaos Vechlidis,Christina Avgoustou,Stamatios Chalvatzis,Miltiades Kyprianou,Jos W. M. van der Meer,Jesper Eugen-Olsen,Mihai G. Netea,Evangelos J. Giamarellos-Bourboulis +38 more
TL;DR: In this article, a blood protein called suPAR (soluble urokinase plasminogen activator receptor) was used to identify patients at the greatest risk of developing severe respiratory failure and requiring a ventilator.
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The early change of SOFA score as a prognostic marker of 28-day sepsis mortality: analysis through a derivation and a validation cohort
Eleni Karakike,Evdoxia Kyriazopoulou,Iraklis Tsangaris,Christina Routsi,Jean Louis Vincent,Evangelos J. Giamarellos-Bourboulis +5 more
TL;DR: ΔSOFA on day 7 is a useful early prognostic marker of 28-day mortality and could serve as an endpoint in future sepsis trials alongside mortality.
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Coronavirus Disease 2019 as Cause of Viral Sepsis: A Systematic Review and Meta-Analysis.
Eleni Karakike,Evangelos J. Giamarellos-Bourboulis,Miltiades Kyprianou,Carolin Fleischmann-Struzek,Mathias W. Pletz,Mihai G. Netea,Konrad Reinhart,Evdoxia Kyriazopoulou +7 more
TL;DR: In this paper, the authors conducted a systematic review on the prevalence of coronavirus disease 2019-related sepsis among adults hospitalized in the ICU and the general ward.
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Transcriptomic Similarities and Differences in Host Response between SARS-CoV-2 and Other Viral Infections
Simone A. Thair,Yudong D He,Yehudit Hasin-Brumshtein,Suraj Sakaram,Rushika Pandya,Jiaying Toh,David Rawling,Melissa Remmel,Sabrina Coyle,George N Dalekos,Ioannis Koutsodimitropoulos,Glykeria Vlachogianni,Eleni Gkeka,Eleni Karakike,Georgia Damoraki,Nikolaos Antonakos,Purvesh Khatri,Evangelos J. Giamarellos-Bourboulis,Timothy E. Sweeney +18 more
TL;DR: The concordant and discordant responses mapped out here provide a window to explore the pathophysiology of the host response to SARS-CoV-2 and reveal dynamic immune evasion and counter host responses specific to COVID-19.