Garyphallia Poulakou

TL;DR: It is found that the plasma colistin concentrations are insufficient before steady state and raise the question of whether the administration of a loading dose would benefit critically ill patients.

TL;DR: Preliminary data show that in patients with severe COVID‐19, anticoagulant therapy appears to be associated with lower mortality in the subpopulation meeting sepsis‐induced coagulopathy criteria or with markedly elevated d‐dimer.

TL;DR: Patients with BSIs due to CPE should receive active therapy as soon as they are diagnosed, and monotherapy should be considered for those in the low-mortality-score stratum.

TL;DR: The emergence of KPC-2-producing K. pneumoniae in Greek hospitals creates an important challenge for clinicians and hospital epidemiologists, because it is added to the already high burden of antimicrobial resistance.

TL;DR: Tigecycline, the first representative of the new class of glycylcyclines, holds promise in infections from MDR K. pneumoniae and Enterobacteriaceae with various mechanisms of resistance and doripenem, the recently licensed member of the carbapenems seems to possess a lower potential for resistance selection and a more favourable pharmacokinetic profile when given as an extended infusion.