G
Georgia Damoraki
Researcher at National and Kapodistrian University of Athens
Publications - 35
Citations - 2345
Georgia Damoraki is an academic researcher from National and Kapodistrian University of Athens. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 11, co-authored 24 publications receiving 1527 citations. Previous affiliations of Georgia Damoraki include Athens State University.
Papers
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Journal ArticleDOI
Complex immune dysregulation in covid-19 patients with severe respiratory failure
Evangelos J. Giamarellos-Bourboulis,Mihai G. Netea,Mihai G. Netea,Nikoletta Rovina,Karolina Akinosoglou,Anastasia Antoniadou,Nikolaos Antonakos,Georgia Damoraki,Theologia Gkavogianni,Maria Evangelia Adami,Paraskevi Katsaounou,Maria Ntaganou,Magdalini Kyriakopoulou,George Dimopoulos,Ioannis Koutsodimitropoulos,Dimitrios Velissaris,Panagiotis Koufargyris,Athanassios Karageorgos,Konstantina Katrini,Vasileios Lekakis,Mihaela Lupse,Antigone Kotsaki,George Renieris,Danai Theodoulou,Vassiliki Panou,Evangelia Koukaki,Nikolaos Koulouris,Charalambos Gogos,Antonia Koutsoukou +28 more
TL;DR: In this paper, the authors found that severe respiratory failure (SRF) in COVID-19 patients is driven by a unique pattern of immune dysfunction, characterized by IL-6-mediated low HLA-DR expression and lymphopenia, associated with sustained cytokine production and hyper-inflammation.
Journal ArticleDOI
Activate: Randomized Clinical Trial of BCG Vaccination against Infection in the Elderly.
Evangelos J. Giamarellos-Bourboulis,Maria Tsilika,Simone J.C.F.M. Moorlag,Nikolaos Antonakos,Antigone Kotsaki,Jorge Domínguez-Andrés,Evdoxia Kyriazopoulou,Theologia Gkavogianni,Maria-Evangelia Adami,Georgia Damoraki,Panagiotis Koufargyris,Athanassios Karageorgos,Amalia Bolanou,Hans J. P. M. Koenen,Reinout van Crevel,Dionyssia-Irene Droggiti,George Renieris,Antonios Papadopoulos,Mihai G. Netea,Mihai G. Netea +19 more
TL;DR: Data show that BCG vaccination is safe and can protect the elderly against infections, and larger studies are needed to assess protection against respiratory infections, including COVID-19.
Journal ArticleDOI
A Four-Probiotics Regimen Reduces Postoperative Complications After Colorectal Surgery: A Randomized, Double-Blind, Placebo-Controlled Study.
Katerina Kotzampassi,George Stavrou,Georgia Damoraki,Marianna Georgitsi,George Basdanis,Georgia Tsaousi,Evangelos J. Giamarellos-Bourboulis +6 more
TL;DR: The studied probiotic formulation significantly decreased the risk of postoperative complications, namely mechanical ventilation, infections and anastomotic leakage.
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Activation of NLRP3 Inflammasome in Inflammatory Bowel Disease: Differences Between Crohn's Disease and Ulcerative Colitis.
Lazaros-Dimitrios Lazaridis,Aikaterini Pistiki,Evangelos J. Giamarellos-Bourboulis,Marianna Georgitsi,Georgia Damoraki,Dimitrios Polymeros,George Dimitriadis,Konstantinos Triantafyllou +7 more
TL;DR: NLRP3 inflammasome is activated in CD patients and in UC patients with long-standing disease and IL-1β production was similar between carriers of wild-type and of SNP alleles of the rs2241880.
Journal ArticleDOI
Transcriptomic Similarities and Differences in Host Response between SARS-CoV-2 and Other Viral Infections
Simone A. Thair,Yudong D He,Yehudit Hasin-Brumshtein,Suraj Sakaram,Rushika Pandya,Jiaying Toh,David Rawling,Melissa Remmel,Sabrina Coyle,George N Dalekos,Ioannis Koutsodimitropoulos,Glykeria Vlachogianni,Eleni Gkeka,Eleni Karakike,Georgia Damoraki,Nikolaos Antonakos,Purvesh Khatri,Evangelos J. Giamarellos-Bourboulis,Timothy E. Sweeney +18 more
TL;DR: The concordant and discordant responses mapped out here provide a window to explore the pathophysiology of the host response to SARS-CoV-2 and reveal dynamic immune evasion and counter host responses specific to COVID-19.