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Theologia Gkavogianni
Researcher at National and Kapodistrian University of Athens
Publications - 24
Citations - 2201
Theologia Gkavogianni is an academic researcher from National and Kapodistrian University of Athens. The author has contributed to research in topics: Inflammation & Sepsis. The author has an hindex of 7, co-authored 18 publications receiving 1356 citations.
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Journal ArticleDOI
Complex immune dysregulation in covid-19 patients with severe respiratory failure
Evangelos J. Giamarellos-Bourboulis,Mihai G. Netea,Mihai G. Netea,Nikoletta Rovina,Karolina Akinosoglou,Anastasia Antoniadou,Nikolaos Antonakos,Georgia Damoraki,Theologia Gkavogianni,Maria Evangelia Adami,Paraskevi Katsaounou,Maria Ntaganou,Magdalini Kyriakopoulou,George Dimopoulos,Ioannis Koutsodimitropoulos,Dimitrios Velissaris,Panagiotis Koufargyris,Athanassios Karageorgos,Konstantina Katrini,Vasileios Lekakis,Mihaela Lupse,Antigone Kotsaki,George Renieris,Danai Theodoulou,Vassiliki Panou,Evangelia Koukaki,Nikolaos Koulouris,Charalambos Gogos,Antonia Koutsoukou +28 more
TL;DR: In this paper, the authors found that severe respiratory failure (SRF) in COVID-19 patients is driven by a unique pattern of immune dysfunction, characterized by IL-6-mediated low HLA-DR expression and lymphopenia, associated with sustained cytokine production and hyper-inflammation.
Journal ArticleDOI
Activate: Randomized Clinical Trial of BCG Vaccination against Infection in the Elderly.
Evangelos J. Giamarellos-Bourboulis,Maria Tsilika,Simone J.C.F.M. Moorlag,Nikolaos Antonakos,Antigone Kotsaki,Jorge Domínguez-Andrés,Evdoxia Kyriazopoulou,Theologia Gkavogianni,Maria-Evangelia Adami,Georgia Damoraki,Panagiotis Koufargyris,Athanassios Karageorgos,Amalia Bolanou,Hans J. P. M. Koenen,Reinout van Crevel,Dionyssia-Irene Droggiti,George Renieris,Antonios Papadopoulos,Mihai G. Netea,Mihai G. Netea +19 more
TL;DR: Data show that BCG vaccination is safe and can protect the elderly against infections, and larger studies are needed to assess protection against respiratory infections, including COVID-19.
Journal ArticleDOI
Macrophage activation-like syndrome: an immunological entity associated with rapid progression to death in sepsis
Evdoxia Kyriazopoulou,Konstantinos Leventogiannis,Anna Norrby-Teglund,Georgios Dimopoulos,Aikaterini Pantazi,Stylianos E. Orfanos,Nikoletta Rovina,Iraklis Tsangaris,Theologia Gkavogianni,Elektra Botsa,Eleftheria Chassiou,Anastasia Kotanidou,Christina Kontouli,Panagiotis Chaloulis,Dimitrios Velissaris,Athina Savva,Jonas-Sundén Cullberg,Karolina Akinosoglou,Charalambos Gogos,Apostolos Armaganidis,Evangelos J. Giamarellos-Bourboulis +20 more
TL;DR: Ferritin measurements can provide early diagnosis of MALS and may allow for specific treatment and be a biomarker of diagnosis and prognosis in sepsis.
Journal ArticleDOI
An open label trial of anakinra to prevent respiratory failure in COVID-19.
Evdoxia Kyriazopoulou,Periklis Panagopoulos,Symeon Metallidis,George N. Dalekos,Garyphallia Poulakou,Nikolaos K. Gatselis,Eleni Karakike,Maria Saridaki,Georgia Loli,Aggelos Stefos,Danai Prasianaki,Sarah P. Georgiadou,Olga Tsachouridou,Vasileios Petrakis,Konstantinos Tsiakos,Maria Kosmidou,Vassiliki Lygoura,Maria Dareioti,Haralampos J. Milionis,Ilias Papanikolaou,Karolina Akinosoglou,Dimitra-Melia Myrodia,Areti Gravvani,Aliki Stamou,Theologia Gkavogianni,Konstantina Katrini,Theodoros Marantos,Ioannis P Trontzas,Konstantinos N. Syrigos,L. Chatzis,Stamatios Chatzis,Nikolaos Vechlidis,Christina Avgoustou,Stamatios Chalvatzis,Miltiades Kyprianou,Jos W. M. van der Meer,Jesper Eugen-Olsen,Mihai G. Netea,Evangelos J. Giamarellos-Bourboulis +38 more
TL;DR: In this article, a blood protein called suPAR (soluble urokinase plasminogen activator receptor) was used to identify patients at the greatest risk of developing severe respiratory failure and requiring a ventilator.
Journal ArticleDOI
Procalcitonin to Reduce Long-Term Infection-associated Adverse Events in Sepsis. A Randomized Trial.
Evdoxia Kyriazopoulou,Lydia Liaskou-Antoniou,George Adamis,Antonia Panagaki,Nikolaos Melachroinopoulos,Elina Drakou,Konstantinos Marousis,Georgios Chrysos,Andronikos Spyrou,Nikolaos Alexiou,Styliani Symbardi,Zoi Alexiou,Styliani Lagou,Virginia Kolonia,Theologia Gkavogianni,Miltiades Kyprianou,Ioannis Anagnostopoulos,Garyfallia Poulakou,Malvina Lada,Anna Makina,Efrosyni Roulia,Marina Koupetori,Vasileios Apostolopoulos,Dimitra Petrou,Thomas Nitsotolis,Anastasia Antoniadou,Evangelos J. Giamarellos-Bourboulis +26 more
TL;DR: In sepsis, PCT guidance was effective in reducing infection-associated adverse events, 28-day mortality, and cost of hospitalization.