G
Gunnar Elke
Researcher at University of Kiel
Publications - 115
Citations - 3971
Gunnar Elke is an academic researcher from University of Kiel. The author has contributed to research in topics: Medicine & Intensive care. The author has an hindex of 26, co-authored 86 publications receiving 2915 citations. Previous affiliations of Gunnar Elke include Keil.
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Journal ArticleDOI
A Randomized Trial of Glutamine and Antioxidants in Critically Ill Patients
Daren K. Heyland,John Muscedere,Paul E. Wischmeyer,Deborah Cook,Gwynne Jones,Martin Albert,Gunnar Elke,Mette M. Berger,Andrew G. Day +8 more
TL;DR: Early provision of glutamine or antioxidants did not improve clinical outcomes, and glutamine was associated with an increase in mortality among critically ill patients with multiorgan failure.
Journal ArticleDOI
Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19.
Joana P. Bernardes,Neha Mishra,Florian Tran,Thomas Bahmer,Lena Best,Johanna I. Blase,Dora Bordoni,Jeanette Franzenburg,Ulf Geisen,Jonathan Josephs-Spaulding,Philipp Köhler,Axel Künstner,Elisa Rosati,Anna C. Aschenbrenner,Petra Bacher,Nathan Baran,Teide Boysen,Burkhard Brandt,Niklas Bruse,Jonathan Dörr,Andreas Dräger,Gunnar Elke,David Ellinghaus,Julia Fischer,Michael Forster,Andre Franke,Sören Franzenburg,Norbert Frey,Anette Friedrichs,Janina Fuß,Andreas Glück,Jacob Hamm,Finn Hinrichsen,Marc P. Hoeppner,Simon Imm,Ralf Junker,Sina Kaiser,Ying H. Kan,Rainer Knoll,Christoph Lange,Georg Laue,Clemens Lier,Matthias Lindner,Georgios Marinos,Robert Markewitz,Jacob Nattermann,Rainer Noth,Peter Pickkers,Klaus F. Rabe,Alina Renz,Christoph Röcken,Jan Rupp,Annika Schaffarzyk,Alexander Scheffold,Jonas Schulte-Schrepping,Jonas Schulte-Schrepping,Domagoj Schunk,Dirk Skowasch,Thomas Ulas,Thomas Ulas,Klaus-Peter Wandinger,Michael Wittig,Johannes Zimmermann,Hauke Busch,Bimba F. Hoyer,Christoph Kaleta,Jan Heyckendorf,Matthijs Kox,Jan Rybniker,Stefan Schreiber,Joachim L. Schultze,Joachim L. Schultze,Philip Rosenstiel,Nicholas E. Banovich,Tushar J. Desai,Oliver Eickelberg,Muzlifa Haniffa,Peter Horvath,Jonathan A. Kropski,Robert Lafyatis,Joakim Lundeberg,Kerstin B. Meyer,Martijn C. Nawijn,Marko Nikolic,Jose Ordovas Montanes,Dana Pe'er,Purushothama Rao Tata,Emma L. Rawlins,Aviv Regev,Paul A. Reyfman,Christos Samakovlis,Joachim Schultze,Alex K. Shalek,Douglas P. Shepherd,Jason R. Spence,Sarah A. Teichmann,Fabian J. Theis,Alexander M. Tsankov,Maarten van den Berge,Michael von Papen,Jeffrey A. Whitsett,Laure-Emmanuelle Zaragosi,Angel Angelov,Robert Bals,Alexander Bartholomäus,Anke Becker,Daniela Bezdan,Ezio Bonifacio,Peer Bork,Thomas Clavel,Maria Colme-Tatche,Andreas Diefenbach,Alexander T. Dilthey,Nicole Fischer,Konrad U. Förstner,Julia-Stefanie Frick,Julien Gagneur,Alexander Goesmann,Torsten Hain,Michael Hummel,Stefan Janssen,Jörn Kalinowski,René Kallies,Birte Kehr,Andreas Keller,Sarah Kim-Hellmuth,Christoph Klein,Oliver Kohlbacher,Jan O. Korbel,Ingo Kurth,Markus Landthaler,Yang Li,Kerstin U. Ludwig,Oliwia Makarewicz,Manja Marz,Alice C. McHardy,Christian Mertes,Markus M. Nöthen,Peter Nürnberg,Uwe Ohler,Stephan Ossowski,Jörg Overmann,Silke Peter,Klaus Pfeffer,Anna R. Poetsch,Alfred Pühler,Niklaus Rajewsky,Markus Ralser,Olaf Rieß,Stephan Ripke,Ulisses Nunes da Rocha,Antoine-Emmanuel Saliba,Leif E. Sander,Birgit Sawitzki,Philipp H. Schiffer,Eva-Christina Schulte,Alexander Sczyrba,Oliver Stegle,Jens Stoye,Janne Vehreschild,Jörg Vogel,Max von Kleist,Andreas Walker,Jörn Walter,Dagmar Wieczorek,John Ziebuhr +165 more
TL;DR: The study demonstrates broad cellular effects of SARS-CoV-2 infection beyond classical immune cells and may serve as an entry point to develop biomarkers and targeted treatments of patients with COVID-19.
Journal ArticleDOI
Enteral versus parenteral nutrition in critically ill patients: an updated systematic review and meta-analysis of randomized controlled trials.
Gunnar Elke,Arthur R. H. van Zanten,Margot Lemieux,Michele McCall,Khursheed N. Jeejeebhoy,Matthias Kott,Xuran Jiang,Andrew G. Day,Daren K. Heyland +8 more
TL;DR: In critically ill patients, the use of EN as compared to PN has no effect on overall mortality but decreases infectious complications and ICU LOS, and a publication bias may be present.
Journal ArticleDOI
Effect of Sodium Selenite Administration and Procalcitonin-Guided Therapy on Mortality in Patients With Severe Sepsis or Septic Shock: A Randomized Clinical Trial.
Frank Bloos,Evelyn Trips,Axel Nierhaus,Josef Briegel,Daren K. Heyland,Ulrich Jaschinski,Onnen Moerer,Andreas Weyland,Gernot Marx,Matthias Gründling,Stefan Kluge,Ines Kaufmann,Klaus Ott,Michael Quintel,Florian Jelschen,Patrick Meybohm,Sibylle Rademacher,Andreas Meier-Hellmann,Stefan Utzolino,Udo Kaisers,Christian Putensen,Gunnar Elke,Maximilian Ragaller,Herwig Gerlach,Katrin Ludewig,Michael Kiehntopf,Holger Bogatsch,Christoph Engel,Frank M. Brunkhorst,Markus Loeffler,Konrad Reinhart +30 more
TL;DR: Neither high-dose intravenous administration of sodium selenite nor anti-infectious therapy guided by a procalcitonin algorithm was associated with an improved outcome in patients with severe sepsis.
Journal ArticleDOI
Close to recommended caloric and protein intake by enteral nutrition is associated with better clinical outcome of critically ill septic patients: secondary analysis of a large international nutrition database
TL;DR: In critically ill septic patients, a calorie and protein delivery closer to recommended amounts by EN in the early phase of ICU stay was associated with a more favorable outcome.