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Eliana Gotti
Researcher at Mario Negri Institute for Pharmacological Research
Publications - 73
Citations - 4226
Eliana Gotti is an academic researcher from Mario Negri Institute for Pharmacological Research. The author has contributed to research in topics: Transplantation & Kidney transplantation. The author has an hindex of 33, co-authored 73 publications receiving 4006 citations. Previous affiliations of Eliana Gotti include University of Milan.
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Journal ArticleDOI
Uraemic bleeding: role of anaemia and beneficial effect of red cell transfusions
TL;DR: Bleeding time, altered in most uraemic patients, may be influenced by packed cell volume (PCV), and the platelet-mediated haemorrhagic tendency in uraemia may be successfully managed by raising PCV values to above 30%.
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Autologous Mesenchymal Stromal Cells and Kidney Transplantation: A Pilot Study of Safety and Clinical Feasibility
Norberto Perico,Federica Casiraghi,Martino Introna,Eliana Gotti,Marta Todeschini,Regiane Aparecida Cavinato,Chiara Capelli,Alessandro Rambaldi,Paola Cassis,Paola Rizzo,Monica Cortinovis,Maddalena Marasa,Josée Golay,Marina Noris,Giuseppe Remuzzi +14 more
TL;DR: Findings from this study in the two patients show that MSC infusion in kidney transplant recipients is feasible, allows enlargement of Treg in the peripheral blood, and controls memory CD8+ T cell function.
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Dynamics of complement activation in aHUS and how to monitor eculizumab therapy
Marina Noris,Miriam Galbusera,Sara Gastoldi,Paolo Macor,Federica Banterla,Elena Bresin,Claudio Tripodo,Serena Bettoni,Roberta Donadelli,Elisabetta Valoti,Francesco Tedesco,Alessandro Amore,Rosanna Coppo,Piero Ruggenenti,Eliana Gotti,Giuseppe Remuzzi +15 more
TL;DR: Results point to efficient complement inhibition on endothelium for aHUS treatment, including C5b-9 endothelial deposits, which might help monitor eculizumab effectiveness, avoid drug overexposure, and save money considering the extremely high cost of the drug.
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Regulatory T Cells and T Cell Depletion: Role of Immunosuppressive Drugs
Marina Noris,Federica Casiraghi,Marta Todeschini,Paolo Cravedi,Daniela Cugini,Giuseppe Monteferrante,Sistiana Aiello,Linda Cassis,Eliana Gotti,Flavio Gaspari,Dario Cattaneo,Norberto Perico,Giuseppe Remuzzi +12 more
TL;DR: Findings from this study will be instrumental in developing "tolerance permissive" immunosuppressive regimens in the clinical setting of renal transplant patients.
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Glucocorticoids interfere with mycophenolate mofetil bioavailability in kidney transplantation
TL;DR: It is indicated that steroids interfere with MPA bioavailability, and that discontinuation of the drug results in higher MPA exposure, which may compensate at least in part for the lower immunosuppressive level achieved with the remaining dual therapy with CsA and MMF.