E
Elizabeth C. Wright
Researcher at National Institutes of Health
Publications - 136
Citations - 14515
Elizabeth C. Wright is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Hepatitis C & Cirrhosis. The author has an hindex of 58, co-authored 130 publications receiving 13690 citations. Previous affiliations of Elizabeth C. Wright include George Washington University & University of Texas Southwestern Medical Center.
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Journal ArticleDOI
Long-term effects of cognitive training on everyday functional outcomes in older adults
Sherry L. Willis,Sharon L. Tennstedt,Michael Marsiske,Karlene Ball,Jeffrey W. Elias,Kathy Mann Koepke,John N. Morris,George W. Rebok,Frederick W. Unverzagt,Anne M. Stoddard,Elizabeth C. Wright +10 more
TL;DR: Cognitive training resulted in improved cognitive abilities specific to the abilities trained that continued 5 years after the initiation of the intervention, and booster training for the speed of processing group showed a significant effect on the performance-based functional measure of everyday speed ofprocessing.
Journal ArticleDOI
Protection from obesity and diabetes by blockade of TGF-β/Smad3 signaling
Hariom Yadav,Celia Quijano,Celia Quijano,Anil K. Kamaraju,Oksana Gavrilova,Rana Malek,Weiping Chen,Patricia M. Zerfas,Duan Zhigang,Elizabeth C. Wright,Christina H. Stuelten,Peter D. Sun,Scott Lonning,Monica C. Skarulis,Anne E. Sumner,Toren Finkel,Sushil G. Rane +16 more
TL;DR: It is demonstrated that TGF-β signaling regulates glucose tolerance and energy homeostasis and suggested that modulation of T GF-β activity might be an effective treatment strategy for obesity and diabetes.
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Acute Chest Syndrome in Sickle Cell Disease: Clinical Presentation and Course
Elliott Vichinsky,Lori Styles,Linda Colangelo,Elizabeth C. Wright,Oswaldo Castro,Bruce G. Nickerson +5 more
TL;DR: In children, ACS was milder and more likely due to infection, whereas in adults ACS was severe, associated with pain and had a higher mortality rate, which was four times higher in adults than in children.
Journal ArticleDOI
Body Weight in Chronic Obstructive Pulmonary Disease: The National Institutes of Health Intermittent Positive-Pressure Breathing Trial
TL;DR: The hypothesis that factors related to nutritional status are an independent influence on the course of COPD is supported, as body weight was a powerful predictor of diffusing capacity in patients with the same FEV1.
Journal ArticleDOI
Peginterferon alfa-2a and ribavirin in patients with chronic hepatitis C who have failed prior treatment.
Mitchell L. Shiffman,Adrian M. Di Bisceglie,Karen L. Lindsay,Chihiro Morishima,Elizabeth C. Wright,Gregory T. Everson,Anna S. Lok,Timothy R. Morgan,Herbert L. Bonkovsky,William M. Lee,Jules L. Dienstag,Marc G. Ghany,Zachary D. Goodman,James E. Everhart +13 more
TL;DR: The most effective therapy currently available for treatment of chronic hepatitis C virus (HCV) is the combination of peginterferon and ribavirin, which was evaluated in patients who were nonresponders to previous interferon-based therapy as discussed by the authors.