E
Elodie Segura
Researcher at PSL Research University
Publications - 78
Citations - 12454
Elodie Segura is an academic researcher from PSL Research University. The author has contributed to research in topics: Dendritic cell & Antigen presentation. The author has an hindex of 34, co-authored 66 publications receiving 10541 citations. Previous affiliations of Elodie Segura include French Institute of Health and Medical Research & Curie Institute.
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Journal ArticleDOI
Membrane vesicles as conveyors of immune responses
TL;DR: The role of membrane vesicles, in particular exosomes, in the communication between immune cells, and between tumour and immune cells is focused on.
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Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny
Martin Guilliams,Florent Ginhoux,Claudia Jakubzick,Shalin H. Naik,Nobuyuki Onai,Barbara U. Schraml,Elodie Segura,Roxane Tussiwand,Simon Yona +8 more
TL;DR: This Opinion article suggests that the mononuclear phagocyte system can be classified primarily by their ontogeny and secondarily by their location, function and phenotype, which permits a more robust classification during both steady-state and inflammatory conditions.
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Cross-presentation by dendritic cells.
Olivier Joffre,Elodie Segura,Elodie Segura,Ariel Savina,Ariel Savina,Sebastian Amigorena,Sebastian Amigorena +6 more
TL;DR: Recent advances in the understanding of the intracellular mechanisms of cross-presentation are summarized and its role in immunity and tolerance in the context of specialization between DC subsets is discussed.
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Indirect activation of naïve CD4 + T cells by dendritic cell–derived exosomes
TL;DR: It is found that injection of antigen- or peptide-bearing exosomes induced antigen-specific naïve CD4+ T cell activation in vivo and may increase the number of DCs bearing a particular peptide, thus amplifying the initiation of primary adaptive immune responses.
Journal ArticleDOI
Human Inflammatory Dendritic Cells Induce Th17 Cell Differentiation
Elodie Segura,Maxime Touzot,Maxime Touzot,Armelle Bohineust,Armelle Bohineust,Antonio Cappuccio,Antonio Cappuccio,Gilles Chiocchia,Gilles Chiocchia,Anne Hosmalin,Marc Dalod,Marc Dalod,Marc Dalod,Vassili Soumelis,Vassili Soumelis,Sebastian Amigorena,Sebastian Amigorena +16 more
TL;DR: It is concluded that inflammatory DCs represent a distinct human DC subset and proposed that they are derived from monocytes and are involved in the induction and maintenance of Th17 cell responses.