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Emilie Mace
Researcher at Max Planck Society
Publications - 33
Citations - 2446
Emilie Mace is an academic researcher from Max Planck Society. The author has contributed to research in topics: Retina & Shear waves. The author has an hindex of 15, co-authored 30 publications receiving 1871 citations. Previous affiliations of Emilie Mace include ESPCI ParisTech & Pierre-and-Marie-Curie University.
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Journal ArticleDOI
Viscoelastic and anisotropic mechanical properties of in vivo muscle tissue assessed by supersonic shear imaging.
TL;DR: The in vivo assessment of the biomechanical properties of the skeletal muscle is a complex issue because the muscle is an anisotropic, viscoelastic and dynamic medium and these mechanical properties are characterized using a noninvasive ultrasound-based technique.
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Functional ultrasound imaging of the brain.
TL;DR: FUS identifies regions of brain activation and was used to image whisker-evoked cortical and thalamic responses and the propagation of epileptiform seizures in the rat brain.
Journal ArticleDOI
Functional ultrasound imaging of the brain: theory and basic principles
TL;DR: A μDoppler ultrasound method able to detect and map the cerebral blood volume (CBV) over the entire brain with an important increase in sensitivity is presented and is the basis for a real-time functional ultrasound (fUS) imaging of the brain.
Journal ArticleDOI
Targeting Channelrhodopsin-2 to ON-bipolar Cells With Vitreally Administered AAV Restores ON and OFF Visual Responses in Blind Mice
Emilie Mace,Emilie Mace,Emilie Mace,Romain Caplette,Romain Caplette,Romain Caplette,Olivier Marre,Olivier Marre,Olivier Marre,Abhishek Sengupta,Abhishek Sengupta,Abhishek Sengupta,Antoine Chaffiol,Antoine Chaffiol,Antoine Chaffiol,Peggy Barbe,Peggy Barbe,Peggy Barbe,Melissa Desrosiers,Melissa Desrosiers,Melissa Desrosiers,Ernst Bamberg,José-Alain Sahel,Serge Picaud,Serge Picaud,Serge Picaud,Jens Duebel,Jens Duebel,Jens Duebel,Deniz Dalkara,Deniz Dalkara,Deniz Dalkara +31 more
TL;DR: The results support the clinical relevance of a minimally invasive AAV-mediated optogenetic therapy for visual restoration and show that AAV encoding channelrhodopsin under the ON bipolar cell-specific promoter mediates long-term gene delivery restricted to ON-bipolar cells after intravitreal administration.
Journal ArticleDOI
Red-shifted channelrhodopsin stimulation restores light responses in blind mice, macaque retina, and human retina.
Abhishek Sengupta,Abhishek Sengupta,Abhishek Sengupta,Antoine Chaffiol,Antoine Chaffiol,Antoine Chaffiol,Emilie Mace,Emilie Mace,Emilie Mace,Romain Caplette,Romain Caplette,Romain Caplette,Melissa Desrosiers,Melissa Desrosiers,Melissa Desrosiers,Maruša Lampič,Maruša Lampič,Maruša Lampič,Valérie Forster,Valérie Forster,Valérie Forster,Olivier Marre,Olivier Marre,Olivier Marre,John Y. Lin,José-Alain Sahel,Serge Picaud,Serge Picaud,Serge Picaud,Deniz Dalkara,Deniz Dalkara,Deniz Dalkara,Jens Duebel,Jens Duebel,Jens Duebel +34 more
TL;DR: It is shown that a red‐shifted channelrhodopsin (ReaChR), delivered by AAV injections in blind rd1 mice, enables restoration of light responses at the retinal, cortical, and behavioral levels, using orange light at intensities below the safety threshold for the human retina.