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Eric R. Tkaczyk
Researcher at United States Department of Veterans Affairs
Publications - 87
Citations - 721
Eric R. Tkaczyk is an academic researcher from United States Department of Veterans Affairs. The author has contributed to research in topics: Medicine & Computer science. The author has an hindex of 12, co-authored 64 publications receiving 500 citations. Previous affiliations of Eric R. Tkaczyk include Vanderbilt University Medical Center & General Electric.
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Journal ArticleDOI
miR-146b Probably Assists miRNA-146a in the Suppression of Keratinocyte Proliferation and Inflammatory Responses in Psoriasis.
H. Hermann,Toomas Runnel,Alar Aab,Hansjörg Baurecht,Elke Rodriguez,Nathaniel Magilnick,Egon Urgard,Liisi Šahmatova,Ele Prans,Julia Maslovskaja,Kristi Abram,Maire Karelson,Bret Kaldvee,Bret Kaldvee,Paula Reemann,Uku Haljasorg,Beate Rückert,Paulina Wawrzyniak,Michael Weichenthal,Ulrich Mrowietz,Andre Franke,Christian Gieger,Jonathan Barker,Richard C. Trembath,Lam C. Tsoi,James T. Elder,Eric R. Tkaczyk,Kai Kisand,Pärt Peterson,Külli Kingo,Külli Kingo,Mark Boldin,Stephan Weidinger,Cezmi A. Akdis,Ana Rebane +34 more
TL;DR: The results indicate that besides miR-146a, miB-146b is expressed and might be capable of modulation of inflammatory responses and keratinocyte proliferation in psoriatic skin.
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National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IIa. The 2020 Clinical Implementation and Early Diagnosis Working Group Report.
Carrie L. Kitko,Joseph Pidala,Hélène Schoemans,Anita Lawitschka,Mary E.D. Flowers,Mary E.D. Flowers,Edward W. Cowen,Eric R. Tkaczyk,Eric R. Tkaczyk,Eric R. Tkaczyk,Nosha Farhadfar,Sandeep Jain,Philipp Steven,Zhonghui K. Luo,Yoko Ogawa,Michael Stern,Greg Yanik,Geoffrey D.E. Cuvelier,Guang-Shing Cheng,Guang-Shing Cheng,Shernan G. Holtan,Kirk R. Schultz,Paul J. Martin,Paul J. Martin,Stephanie J. Lee,Stephanie J. Lee,Steven Z. Pavletic,Daniel Wolff,Sophie Paczesny,Bruce R. Blazar,Stephanie Sarantopoulos,Gérard Socié,Hildegard Greinix,Corey Cutler +33 more
TL;DR: In this article, the authors provide consensus recommendations regarding implementation of the current NIH diagnostic guidelines into routine transplant care, outside of clinical trials, aiming to enhance early clinical recognition of chronic GVHD.
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Kinetic properties of ASC protein aggregation in epithelial cells.
Jun Cheng,Andrea L. Waite,Eric R. Tkaczyk,Kevin Ke,Neil Richards,Alan J. Hunt,Deborah L. Gumucio +6 more
TL;DR: Comparing kinetic models of the aggregation process indicates diffusion, instead of active transport, is the dominant process for speck growth, and it is shown that the two processes are distinct.
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Pre-administration of PepFect6-microRNA-146a nanocomplexes inhibits inflammatory responses in keratinocytes and in a mouse model of irritant contact dermatitis.
Egon Urgard,Annely Lorents,Mariliis Klaas,Kärt Padari,Janeli Viil,Toomas Runnel,Kent Langel,Külli Kingo,Eric R. Tkaczyk,Ülo Langel,Toivo Maimets,Viljar Jaks,Margus Pooga,Ana Rebane +13 more
TL;DR: PF6-miR-146a nanoparticles might have potential in the development of therapeutics to target inflammatory skin diseases by attenuating ear-swelling and reducing the expression of pro-inflammatory cytokines and chemokines IL-6, CCL11, C CL24 and C-X-C motif ligand 1 (CXCL1) in a mouse model of irritant contact dermatitis.
Journal ArticleDOI
In Vivo Monitoring of Multiple Circulating Cell Populations Using Two-photon Flow Cytometry.
Eric R. Tkaczyk,Cheng Frank Zhong,Jing Yong Ye,Andrzej Myc,Thommey P. Thomas,Zhengyi Cao,Raimon Duran-Struuck,Kathryn E. Luker,Gary D. Luker,Theodore B. Norris,James R. Baker +10 more
TL;DR: This work uses a novel optical system for two-channel, two-photon flow cytometry in vivo to investigate the circulation dynamics in live animals of breast cancer cells with low and high metastatic potential, showing for the first time that two different populations of circulating cells can be quantified simultaneously in the vasculature of a single live mouse.