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Beate Rückert

Researcher at Swiss Institute of Allergy and Asthma Research

Publications -  63
Citations -  4952

Beate Rückert is an academic researcher from Swiss Institute of Allergy and Asthma Research. The author has contributed to research in topics: Immune system & FOXP3. The author has an hindex of 27, co-authored 52 publications receiving 4223 citations. Previous affiliations of Beate Rückert include University of Zurich.

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IgG4 production is confined to human IL-10–producing regulatory B cells that suppress antigen-specific immune responses

TL;DR: The characterization of IL-10+ BR1 cells and in vivo evidence for 2 essential features of allergen tolerance: the suppressive B cells and IgG4-expressing B cells that are confined to IL- 10+BR1 cells in human subjects are shown.
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Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma

TL;DR: Findings demonstrate that glucocorticoid treatment is not only immunosuppressive and anti-inflammatory but also promotes or initiates differentiation toward T R 1 cells by a FOXP3-dependent mechanism.
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Guidelines for the use of flow cytometry and cell sorting in immunological studies

Andrea Cossarizza, +246 more
TL;DR: A rapid search in PubMed shows that using "flow cytometry immunology" as a search term yields more than 68 000 articles, the first of which is not about lymphocytes as mentioned in this paper.
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In vivo switch to IL-10-secreting T regulatory cells in high dose allergen exposure

TL;DR: Rapid switch and expansion of IL-10–producing Tr1 cells and the use of multiple suppressive factors represent essential mechanisms in immune tolerance to a high dose of allergens in nonallergic individuals.
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Molecular Mechanisms Underlying FOXP3 Induction in Human T Cells

TL;DR: The study identifies essential, positive regulators of the FOXP3 gene and highlights cyclosporin A as an inhibitor ofFOXP3 expression contrasting other immunosuppressants such as steroids or rapamycin.