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Erkki Ville Wirta
Publications - 4
Citations - 68
Erkki Ville Wirta is an academic researcher. The author has contributed to research in topics: DNA methylation & Epigenetics. The author has an hindex of 2, co-authored 4 publications receiving 5 citations.
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Journal ArticleDOI
Genetic and Epigenetic Characteristics of Inflammatory Bowel Disease–Associated Colorectal Cancer
Kristiina Rajamäki,Aurora Taira,Riku Katainen,Niko Välimäki,Anna Kuosmanen,Roosa Maria Plaketti,Toni T. Seppälä,Toni T. Seppälä,Toni T. Seppälä,Maarit Ahtiainen,Erkki Ville Wirta,Emilia Vartiainen,Päivi Sulo,Janne J. Ravantti,Suvi Lehtipuro,Kirsi J. Granberg,Matti Nykter,Tomas Tanskanen,Ari Ristimäki,Selja Koskensalo,Laura Renkonen-Sinisalo,Anna Lepistö,Jan Böhm,Jussi Taipale,Jukka-Pekka Mecklin,Mervi Aavikko,Kimmo Palin,Lauri A. Aaltonen +27 more
TL;DR: In this article, the authors comprehensively characterize IBD-associated tumorigenesis integrating multiple high-throughput approaches, and compare the results with in-house data sets from sCRCs.
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Immune Contexture of MMR-Proficient Primary Colorectal Cancer and Matched Liver and Lung Metastases.
Maarit Ahtiainen,Hanna Elomaa,Juha P. Väyrynen,Erkki Ville Wirta,Teijo Kuopio,Olli Helminen,Toni T. Seppälä,Ilmo Kellokumpu,Jukka-Pekka Mecklin +8 more
TL;DR: In this paper, the authors evaluated immune cell infiltration, the programmed death-1/programmed death ligand-1 expression and their prognostic value in a series of mismatch proficient (pMMR) CRC patients with matched liver and lung metastases.
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Impact of Age and Comorbidity on Multimodal Management and Survival from Colorectal Cancer : A Population-Based Study
Ilmo Kellokumpu,Matti V. Kairaluoma,Jukka-Pekka Mecklin,Henrik Kellokumpu,Ville Väyrynen,Erkki Ville Wirta,Eero Sihvo,Teijo Kuopio,Toni T. Seppälä,Toni T. Seppälä +9 more
TL;DR: In this paper, the authors examined the impact of age and comorbidity burden on multimodal management and survival from colorectal cancer (CRC) from 2000 to 2015.
Journal ArticleDOI
Immunoprofiles and DNA Methylation of Inflammatory Marker Genes in Ulcerative Colitis-Associated Colorectal Tumorigenesis
Satu Mäki-Nevala,Sanjeevi Ukwattage,Erkki Ville Wirta,Maarit Ahtiainen,Ari Ristimäki,Toni T. Seppälä,Anna Lepistö,Jukka-Pekka Mecklin,Päivi Peltomäki +8 more
TL;DR: In this paper, the authors determined the immunoprofiles and promoter methylation of inflammation-related genes for colitis-associated colorectal carcinomas (CA-CRC).