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Esteban G. Burchard
Researcher at University of California, San Francisco
Publications - 372
Citations - 43148
Esteban G. Burchard is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Population & Asthma. The author has an hindex of 79, co-authored 347 publications receiving 32449 citations. Previous affiliations of Esteban G. Burchard include University College London & University of Copenhagen.
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Journal ArticleDOI
A meta-analysis of genome-wide association studies for serum total IgE in diverse study populations
Albert M. Levin,Rasika A. Mathias,Liling Huang,Lindsey A. Roth,Denise Daley,Rachel A. Myers,Blanca E. Himes,Isabelle Romieu,Mao Yang,Celeste Eng,Julie E. Park,Karla Zoratti,Christopher R. Gignoux,Dara G. Torgerson,Joshua Galanter,Scott Huntsman,Elizabeth A. Nguyen,Allan B. Becker,Moira Chan-Yeung,Anita L. Kozyrskyj,Anita L. Kozyrskyj,Pui-Yan Kwok,Frank D. Gilliland,W. James Gauderman,Eugene R. Bleecker,Benjamin A. Raby,Deborah A. Meyers,Stephanie J. London,Fernando D. Martinez,Scott T. Weiss,Esteban G. Burchard,Dan L. Nicolae,Carole Ober,Kathleen C. Barnes,L. Keoki Williams +34 more
TL;DR: A meta-analysis independently identified a variant near HLA-DQB1 as a predictor of total serum IgE levels in multiple race-ethnic groups and extends and confirms the findings of earlier genome-wide association analyses in African American and Latino subjects.
Journal ArticleDOI
Native American gene flow into Polynesia predating Easter Island settlement.
Alexander G. Ioannidis,Alexander G. Ioannidis,Javier Blanco-Portillo,Karla Sandoval,Erika Hagelberg,Juan Francisco Miquel-Poblete,J. Víctor Moreno-Mayar,Juan Esteban Rodríguez-Rodríguez,Consuelo D. Quinto-Cortés,Kathryn Auckland,Tom Parks,Kathryn J. H. Robson,Adrian V. S. Hill,María C. Ávila-Arcos,Alexandra Sockell,Julian R. Homburger,Genevieve L. Wojcik,Kathleen C. Barnes,Luisa Herrera,Soledad Berríos,M. Acuña,Elena Llop,Celeste Eng,Scott Huntsman,Esteban G. Burchard,Christopher R. Gignoux,Lucía Cifuentes,Ricardo A. Verdugo,Mauricio Moraga,Alexander J. Mentzer,Carlos Bustamante,Andrés Moreno-Estrada +31 more
TL;DR: Genomic analyses of DNA from modern individuals show that, about 800 years ago, pre-European contact occurred between Polynesian-individuals and Native American individuals from near present-day Colombia, while remote Pacific islands were still being settled.
Journal ArticleDOI
Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis
Supinda Bunyavanich,Eric E. Schadt,Blanca E. Himes,Jessica Lasky-Su,Weiliang Qiu,Ross Lazarus,John Ziniti,Ariella Cohain,Michael D. Linderman,Dara G. Torgerson,Celeste Eng,Maria Pino-Yanes,Maria Pino-Yanes,Badri Padhukasahasram,James J. Yang,Rasika A. Mathias,Terri H. Beaty,Xingnan Li,Penelope E. Graves,Isabelle Romieu,Blanca E. del Rio Navarro,M Towhid Salam,Hita Vora,Dan L. Nicolae,Carole Ober,Fernando D. Martinez,Eugene R. Bleecker,Deborah A. Meyers,W. James Gauderman,Frank D. Gilliland,Esteban G. Burchard,Kathleen C. Barnes,L. Keoki Williams,Stephanie J. London,Bin Zhang,Benjamin A. Raby,Scott T. Weiss +36 more
TL;DR: The integrated approach can be applied to provide biologic context for GWAS of other diseases and highlight mitochondrial pathways as a target for further investigation of allergic rhinitis mechanism and treatment.
Posted ContentDOI
Type 2 and interferon inflammation strongly regulate SARS-CoV-2 related gene expression in the airway epithelium
Satria Sajuthi,Peter DeFord,Nathan D. Jackson,M.T. Montgomery,Jamie L. Everman,Cydney Rios,Elmar Pruesse,James D. Nolin,Elizabeth G. Plender,Michael E. Wechsler,A.C.Y. Mak,Celeste Eng,Sandra Salazar,Vivian Medina,Eric M. Wohlford,Scott Huntsman,Deborah A. Nickerson,Soren Germer,Michael C. Zody,Gonçalo R. Abecasis,Hyun Min Kang,Kenneth Rice,Rajesh Kumar,Sam S. Oh,Jose R. Rodriguez-Santana,Esteban G. Burchard,Max A. Seibold +26 more
TL;DR: Airway responses to coronavirus infections in children are defined, finding that these infections upregulate IL6 while also stimulating a more pronounced cytotoxic immune response relative to other respiratory viruses.
Journal ArticleDOI
GSNO Reductase and β2 Adrenergic Receptor Gene-gene Interaction: Bronchodilator Responsiveness to Albuterol
Shweta Choudhry,Loretta G. Que,Zhonghui Yang,Limin Liu,Celeste Eng,Sung O. Kim,Gunjan Kumar,Shannon Thyne,Rocio Chapela,Jose R. Rodriguez-Santana,William Rodriguez-Cintron,Pedro C. Avila,Jonathan S. Stamler,Esteban G. Burchard +13 more
TL;DR: Genotyping of GSNOR and β2AR genes may be useful in identifying Latino individuals, who might benefit from adjuvant therapy for refractory asthma.