L
Lindsey A. Roth
Researcher at University of California, San Francisco
Publications - 26
Citations - 2464
Lindsey A. Roth is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Genome-wide association study & Single-nucleotide polymorphism. The author has an hindex of 23, co-authored 25 publications receiving 2232 citations.
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Journal ArticleDOI
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations
Dara G. Torgerson,Dara G. Torgerson,Elizabeth J. Ampleford,Grace Y. Chiu,W. James Gauderman,Christopher R. Gignoux,Penelope E. Graves,Blanca E. Himes,Albert M. Levin,Rasika A. Mathias,Dana B. Hancock,Dana B. Hancock,Dana B. Hancock,James W. Baurley,Celeste Eng,Debra A. Stern,Juan C. Celedón,Nicholas Rafaels,Daniel Capurso,David V. Conti,Lindsey A. Roth,Manuel Soto-Quiros,Alkis Togias,Xingnan Li,Rachel A. Myers,Isabelle Romieu,Isabelle Romieu,David Van Den Berg,Donglei Hu,Nadia N. Hansel,Ryan D. Hernandez,Elliott Israel,Muhammad T. Salam,Joshua Galanter,Pedro C. Avila,Lydiana Avila,Jose R. Rodriquez-Santana,R. Chapela,William Rodríguez-Cintrón,Gregory B. Diette,N. Franklin Adkinson,Rebekah A. Abel,K. Ross,Min Shi,Mezbah U. Faruque,Georgia M. Dunston,Harold Watson,Vito J. Mantese,Serpil C. Ezurum,Liming Liang,Ingo Ruczinski,Jean G. Ford,Scott Huntsman,Kian Fan Chung,Hita Vora,Xia Li,William J. Calhoun,Mario Castro,Juan José Luis Sienra-Monge,Blanca Estela Del Río-Navarro,Klaus A. Deichmann,Andrea Heinzmann,Sally E. Wenzel,William W. Busse,William W. Busse,James E. Gern,Robert F. Lemanske,Terri H. Beaty,Eugene R. Bleecker,Benjamin A. Raby,Deborah A. Meyers,Stephanie J. London,Frank D. Gilliland,Esteban G. Burchard,Fernando D. Martinez,Scott T. Weiss,L. Keoki Williams,Kathleen C. Barnes,Carole Ober,Dan L. Nicolae +79 more
TL;DR: The results suggest that some asthma susceptibility loci are robust to differences in ancestry when sufficiently large samples sizes are investigated, and that ancestry-specific associations also contribute to the complex genetic architecture of asthma.
Journal ArticleDOI
Early-Life air pollution and asthma risk in minority children the GALA II and SAGE II studies
Katherine K. Nishimura,Joshua Galanter,Lindsey A. Roth,Sam S. Oh,Neeta Thakur,Elizabeth A. Nguyen,Shannon Thyne,Harold J. Farber,Denise Serebrisky,Rajesh Kumar,Emerita Brigino-Buenaventura,Adam Davis,Michael A. LeNoir,Kelley Meade,William Rodriguez-Cintron,Pedro C. Avila,Luisa N. Borrell,Kirsten Bibbins-Domingo,Jose R. Rodriguez-Santana,Śaunak Sen,Fred Lurmann,John R. Balmes,John R. Balmes,Esteban G. Burchard +23 more
TL;DR: Early-life NO₂ exposure is associated with childhood asthma in Latinos and African Americans, adding to a growing body of evidence that traffic-related pollutants may be causally related to childhood asthma.
Journal ArticleDOI
Dissecting childhood asthma with nasal transcriptomics distinguishes subphenotypes of disease
Alex Poole,Cydney Urbanek,Celeste Eng,Jeoffrey Schageman,Sean Jacobson,Brian P. O'Connor,Joshua Galanter,Christopher R. Gignoux,Lindsey A. Roth,Rajesh Kumar,Sharon M. Lutz,Andrew H. Liu,Tasha E. Fingerlin,Robert Setterquist,Esteban G. Burchard,Jose R. Rodriguez-Santana,Max A. Seibold +16 more
TL;DR: Nasal expression profiling can be used to identify subjects with IL13-driven asthma and a TH2-skewed systemic immune response and largely recapitulate expression profiles in the lung airways.
Journal ArticleDOI
Childhood obesity and asthma control in the GALA II and SAGE II studies.
Luisa N. Borrell,Elizabeth A. Nguyen,Lindsey A. Roth,Sam S. Oh,Haig Tcheurekdjian,Saunak Sen,Adam Davis,Harold J. Farber,Pedro C. Avila,Emerita Brigino-Buenaventura,Michael A. LeNoir,Fred Lurmann,Kelley Meade,Denise Serebrisky,William Rodriguez-Cintron,Rajesh Kumar,Jose R. Rodriguez-Santana,Shannon Thyne,Esteban G. Burchard +18 more
TL;DR: Worse asthma control is uniformly associated with increased body mass index in boys and among girls, the direction of this association varied with race/ethnicity.
Journal ArticleDOI
Genetic ancestry influences asthma susceptibility and lung function among Latinos
Maria Pino-Yanes,Neeta Thakur,Christopher R. Gignoux,Joshua Galanter,Lindsey A. Roth,Celeste Eng,Katherine K. Nishimura,Sam S. Oh,Hita Vora,Scott Huntsman,Elizabeth A. Nguyen,Donglei Hu,Katherine A. Drake,David V. Conti,Andrés Moreno-Estrada,Karla Sandoval,Cheryl A. Winkler,Luisa N. Borrell,Fred Lurmann,Talat Islam,Adam Davis,Harold J. Farber,Kelley Meade,Pedro C. Avila,Denise Serebrisky,Kirsten Bibbins-Domingo,Michael A. LeNoir,Jean G. Ford,Emerita Brigino-Buenaventura,William Rodriguez-Cintron,Shannon Thyne,Saunak Sen,Jose R. Rodriguez-Santana,Carlos Bustamante,L. Keoki Williams,Frank D. Gilliland,W. James Gauderman,Rajesh Kumar,Dara G. Torgerson,Esteban G. Burchard +39 more
TL;DR: For example, the authors found that Native American ancestry was associated with lower odds of asthma (OR = 0.72, 95% CI: 0.66-0.78, P ǫ= 8.0 × 10 −15 ), while African ancestry was significantly associated with higher odds of having asthma.