Esther T. Chan

TL;DR: The Saccharomyces Genome Database is an encyclopedia of the yeast genome, its chromosomal features, their functions and interactions, and public access to these data is provided to researchers and educators via web pages designed for optimal ease of use.

TL;DR: The encyclopedia of DNA elements (ENCODE) Data Coordinating Center has developed the ENCODE Portal database and website as the source for the data and metadata generated by the Encode Consortium as discussed by the authors.

TL;DR: A broad survey of transcription factors reveals that related proteins can have multiple and differing DNA binding specificities, which may be important in gene regulation and in the evolution of transcriptional regulatory networks.

TL;DR: A computational system is developed that successfully predicts binding sites for homeodomain proteins as distant from mouse as Drosophila and C. elegans, and the results provide an unprecedented level of resolution in the analysis of this simple domain structure and suggest that variation in sequence recognition may be a factor in its functional diversity and evolutionary success.

TL;DR: Systematic determination of yeast transcription factor DNA-binding specificities shows that Rsc3 plays a broad role in targeting nucleosome exclusion at yeast promoters, suggesting a role in promoter architecture.