E
Eugenio Fernandez
Researcher at Geneva College
Publications - 13
Citations - 1343
Eugenio Fernandez is an academic researcher from Geneva College. The author has contributed to research in topics: Talimogene laherparepvec & Pembrolizumab. The author has an hindex of 7, co-authored 12 publications receiving 989 citations.
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Journal ArticleDOI
Oncolytic Virotherapy Promotes Intratumoral T Cell Infiltration and Improves Anti-PD-1 Immunotherapy
Antoni Ribas,Reinhard Dummer,Igor Puzanov,Ari M. Vanderwalde,Robert H.I. Andtbacka,Olivier Michielin,Anthony J. Olszanski,Josep Malvehy,Jonathan Cebon,Eugenio Fernandez,John M. Kirkwood,Thomas F. Gajewski,Lisa Chen,Kevin S. Gorski,Abraham Anderson,Scott J. Diede,Michael E. Lassman,Jennifer Gansert,F. Stephen Hodi,Georgina V. Long +19 more
TL;DR: The findings suggest that oncolytic virotherapy may improve the efficacy of anti-PD-1 therapy by changing the tumor microenvironment.
Journal ArticleDOI
Efficacy analysis of MASTERKEY-265 phase 1b study of talimogene laherparepvec (T-VEC) and pembrolizumab (pembro) for unresectable stage IIIB-IV melanoma.
Georgina V. Long,Reinhard Dummer,Antoni Ribas,Igor Puzanov,Ari M. Vanderwalde,Robert H.I. Andtbacka,Olivier Michielin,Anthony J. Olszanski,Josep Malvehy,Jonathan Cebon,Eugenio Fernandez,John M. Kirkwood,Thomas F. Gajewski,Christine K. Gause,Lisa Chen,Kevin S. Gorski,Abraham Anderson,David Ross Kaufman,Jeffrey Chou,F. Stephen Hodi +19 more
TL;DR: T-VEC significantly improved durable response rate vs GM-CSF in stage IIIB-IV melanoma patients (pts) with injectable tumors and the combination may further improve clinical benefit.
Journal ArticleDOI
Erratum: Oncolytic Virotherapy Promotes Intratumoral T Cell Infiltration and Improves Anti-PD-1 Immunotherapy (Cell (2017) 170(6) (1109–1119.e10) (S0092867417309522) (10.1016/j.cell.2017.08.027))
Antoni Ribas,Reinhard Dummer,Igor Puzanov,Ari M. Vanderwalde,Robert H.I. Andtbacka,Olivier Michielin,Anthony J. Olszanski,Josep Malvehy,Jonathan Cebon,Eugenio Fernandez,John M. Kirkwood,Thomas F. Gajewski,Lisa Chen,Kevin S. Gorski,Abraham Anderson,Scott J. Diede,Michael E. Lassman,Jennifer Gansert,F. Stephen Hodi,Georgina V. Long +19 more
Journal ArticleDOI
A Phase I/III, multicenter, open-label trial of talimogene laherparepvec (T-VEC) in combination with pembrolizumab for the treatment of unresected, stage IIIb-IV melanoma (MASTERKEY-265)
Georgina V. Long,Reinhard Dummer,Antoni Ribas,Igor Puzanov,Olivier Michielin,Ari M. Vanderwalde,Robert H.I. Andtbacka,Jonathan Cebon,Eugenio Fernandez,Josep Malvehy,Anthony J. Olszanski,Thomas F. Gajewski,John M. Kirkwood,Olga M. Kuznetsova,Lisa Chen,David Ross Kaufman,Jeffrey Chou,F. Stephen Hodi +17 more
TL;DR: T-VEC is a herpes simplex virus-1-based oncolytic immunotherapy designed to selectively replicate in tumors, produce GM-CSF, and stimulate antitumor immune responses.
Journal ArticleDOI
24LBA Safety data from the phase 1b part of the MASTERKEY-265 study combining talimogene laherparepvec (T-VEC) and pembrolizumab for unresectable stage IIIB-IV melanoma
Georgina V. Long,Reinhard Dummer,A. Ribas,I. Puzanov,Olivier Michielin,Ari M. Vanderwalde,Robert H.I. Andtbacka,Jonathan Cebon,Eugenio Fernandez,Josep Malvehy,Anthony J. Olszanski,Thomas F. Gajewski,John M. Kirkwood,Christine K. Gause,L. Chen,David Ross Kaufman,J. Chou,F.S. Hodi +17 more