E
Eva M. Schmid
Researcher at University of California, Berkeley
Publications - 27
Citations - 1945
Eva M. Schmid is an academic researcher from University of California, Berkeley. The author has contributed to research in topics: Phagocytosis & Signal transducing adaptor protein. The author has an hindex of 15, co-authored 26 publications receiving 1658 citations. Previous affiliations of Eva M. Schmid include Medical University of Vienna & University of California.
Papers
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Journal ArticleDOI
Size-dependent protein segregation at membrane interfaces.
Eva M. Schmid,Matthew H. Bakalar,Kaushik Choudhuri,Julian Weichsel,Hyoung Sook Ann,Phillip L. Geissler,Michael L. Dustin,Daniel A. Fletcher +7 more
TL;DR: It is shown that size differences between binding and non-binding proteins can dramatically alter their organization at membrane interfaces in the absence of active contributions from the cytoskeleton, with as little as a ~5 nm increase in non- binding protein size driving its exclusion from the interface.
Journal ArticleDOI
Size-Dependent Segregation Controls Macrophage Phagocytosis of Antibody-Opsonized Targets.
Matthew H. Bakalar,Aaron M. Joffe,Aaron M. Joffe,Eva M. Schmid,Sungmin Son,Marija Podolski,Daniel A. Fletcher +6 more
TL;DR: It is shown that close contact between macrophage and target is a requirement for efficient phagocytosis, suggesting that therapeutic antibodies should target short antigens in order to trigger Fc receptor activation through size-dependent physical segregation.
Book ChapterDOI
Reconstitution of proteins on electroformed giant unilamellar vesicles.
TL;DR: This synthetic membrane-based approach to reconstitution offers the ability to study protein organization and activity at membranes under more cell-like conditions, addressing a central challenge to accomplishing the grand goal of "building the cell."
Journal ArticleDOI
The Conserved Isoleucine–Valine–Phenylalanine Motif Couples Activation State and Endocytic Functions of β‐Arrestins
Anne Burtey,Anne Burtey,Eva M. Schmid,Marijn G. J. Ford,Joshua Z. Rappoport,Mark G.H. Scott,Mark G.H. Scott,Stefano Marullo,Stefano Marullo,Sanford M. Simon,Harvey T. McMahon,Alexandre Benmerah,Alexandre Benmerah +12 more
TL;DR: Structural, biochemical and functional evidence is provided in living cells that the IVF motif also controls binding to AP‐2, resulting in active βarr mutants, which are constitutively targeted to CCPs in the absence of any GPCR activation.
Journal ArticleDOI
Quantitative biophysical analysis defines key components modulating recruitment of the GTPase KRAS to the plasma membrane
Bindu Lakshman,Simon Messing,Eva M. Schmid,Jeffrey D. Clogston,William K. Gillette,Dominic Esposito,Bailey Kessing,Daniel A. Fletcher,Daniel A. Fletcher,Dwight V. Nissley,Frank McCormick,Frank McCormick,Andrew G. Stephen,Frantz L. Jean-Francois +13 more
TL;DR: It is found that the RAF1 region spanning RBD through CRD (RBDCRD) interacts with the membrane significantly more strongly than the isolated RBD or CRD domains and synergizes KRAS partitioning to the membrane.