F
Fabienne Parente
Researcher at Centre national de la recherche scientifique
Publications - 7
Citations - 935
Fabienne Parente is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Gene & MEN1. The author has an hindex of 6, co-authored 7 publications receiving 907 citations.
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Journal ArticleDOI
Identification of the Multiple Endocrine Neoplasia Type 1 (MEN1) Gene. The European Consortium on MEN1
Irma Lemmens,Wim J.M. Van de Ven,Koen Kas,Chang X. Zhang,Sophie Giraud,Virginie Wautot,Nathalie Buisson,Ko De Witte,Janine Salandre,Gilbert M. Lenoir,Michel Pugeat,Alain Calender,Fabienne Parente,Danielle Quincey,Patrick Gaudray,Mireille J. De Wit,Cornelis J.M. Lips,Jo W.M. Höppener,Shideh Khodaei,Abby L. Grant,Günther Weber,Soili Kytölä,Bin Tean Teh,Filip Farnebo,Catherine M. Phelan,Nicholas K. Hayward,Catharina Larsson,Anna A.J. Pannett,Simon A. Forbes,J. H. Duncan Bassett,Rajesh V. Thakker +30 more
TL;DR: Mutational analysis of SCG2 in 10 unrelated MEN1 families identified one polymorphism and nine different heterozygous mutations that segregated with the disease, hence providing an independent confirmation for the identification of the MEN1 gene.
Journal ArticleDOI
Mutation analysis of the MEN1 gene in multiple endocrine neoplasia type 1, familial acromegaly and familial isolated hyperparathyroidism
Bin Tean Teh,Soili Kytölä,Filip Farnebo,L. Bergman,Fung Ki Wong,Günther Weber,Nicholas K. Hayward,Catharina Larsson,Britt Skogseid,Albert Beckers,Catherine M. Phelan,Matthew S. Edwards,M. Epstein,Frank P. Alford,D Hurley,Sean M. Grimmond,Ginters Silins,Marilyn K. Walters,Christine Stewart,John Cardinal,Shideh Khodaei,Fabienne Parente,L. Tranebjærg,R. Jorde,J. Menon,A. Khir,T. T. Tan,Siew Pheng Chan,A. Zaini,B. A. K. Khalid,Kerstin Sandelin,Norman W. Thompson,M. L. Brandi,M. Warth,John L. Stock,J. Leisti,David Cameron,Joseph J. Shepherd,Kjell Öberg,Magnus Nordenskjöld,Pasi I. Salmela +40 more
TL;DR: No mutation was found in any of the acromegaly and small FIHP families, suggesting that genetic defects other than the MEN1 gene might be involved and that additional such families need to be analyzed.
Journal ArticleDOI
Characterization of the mouse Men1 gene and its expression during development.
Christine Stewart,Fabienne Parente,Fredrik Piehl,Filip Farnebo,Danielle Quincey,Ginters Silins,L. Bergman,George Carle,Irma Lemmens,Sean M. Grimmond,Chang Zhang Xian,Shideh Khodei,Bin Tean Teh,Jacob Lagercrantz,Pamela Siggers,Alain Calender,Vim Van de Vem,Koen Kas,Günther Weber,Nicholas K. Hayward,Patrick Gaudray,Catharina Larsson +21 more
TL;DR: The results show that MEN1 expression is not confined to organs affected in MEN1, suggesting that Men1 has a significant function in many different cell types including the CNS and testis.
Journal ArticleDOI
Construction of a 1.2-Mb sequence-ready contig of chromosome 11q13 encompassing the multiple endocrine neoplasia type 1 (MEN1) gene. The European Consortium on MEN1.
Irma Lemmens,Jozef Merregaert,Wim J.M. Van de Ven,Koen Kas,Chang X. Zhang,Sophie Giraud,Virginie Wautot,Nathalie Buisson,Ko De Witte,Janine Salandre,Gilbert M. Lenoir,Alain Calender,Fabienne Parente,Danielle Quincey,Anouk Courseaux,George Carle,Patrick Gaudray,Mireille J. De Wit,Cornelis J.M. Lips,Jo W.M. Höppener,Shideh Khodaei,Abby L. Grant,Günther Weber,Soili Kytölä,Bin Tean Teh,Filip Farnebo,Sean M. Grimmond,Catherine M. Phelan,Catharina Larsson,Simon A. Forbes,J. H. Duncan Bassett,Anna A.J. Pannett,Rajesh V. Thakker +32 more
TL;DR: A valuable transcriptional map of chromosome 11q13 that will help in the search for disease genes in this region is presented, and a 1200-kb sequence-ready contig consisting of 26 cosmids, eight BACs, and eight PACs that encompass this region are established.
Journal ArticleDOI
Expression and chromosomal localization of the Requiem gene
Theodore G. Gabig,Colin D. Crean,Alison Klenk,Haiyan Long,Neal G. Copeland,Debra J. Gilbert,Nancy A. Jenkins,Danielle Quincey,Fabienne Parente,Françoise Lespinasse,Georges F. Carle,Patrick Gaudray,Chang X. Zhang,Alain Calender,Jo Hoeppener,Koen Kas,Rajesh V. Thakker,Filip Farnebo,Bin Tean Teh,Catharina Larsson,Fredrik Piehl,Jacob Lagercrantz,Shideh Khodaei,Emma Carson,Günther Weber +24 more
TL;DR: The spatio-temporal expression pattern in the mouse is consistent with a functional role during rapid growth and cell turnover, and in agreement with a regulatory function for hematopoietic cells.