F
Fabienne Paumet
Researcher at Thomas Jefferson University
Publications - 28
Citations - 2481
Fabienne Paumet is an academic researcher from Thomas Jefferson University. The author has contributed to research in topics: Lipid bilayer fusion & Exocytosis. The author has an hindex of 19, co-authored 27 publications receiving 2336 citations. Previous affiliations of Fabienne Paumet include Columbia University & Columbia University Medical Center.
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Journal ArticleDOI
Compartmental specificity of cellular membrane fusion encoded in SNARE proteins
James A. McNew,Francesco Parlati,Ryouichi Fukuda,Robert J. Johnston,Keren Paz,Fabienne Paumet,Thomas H. Söllner,James E. Rothman +7 more
TL;DR: It is found that, to a marked degree, the pattern of membrane flow in the cell is encoded and recapitulated by its isolated SNARE proteins, as predicted by the SNARE hypothesis.
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Selective Activation of Cognate SNAREpins by Sec1/Munc18 Proteins
TL;DR: A fundamental role is demonstrated of the SM protein: to act as a stimulatory subunit of its cognate SNARE fusion machinery, enhancing fusion specificity in a reconstituted system.
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Soluble NSF Attachment Protein Receptors (SNAREs) in RBL-2H3 Mast Cells: Functional Role of Syntaxin 4 in Exocytosis and Identification of a Vesicle-Associated Membrane Protein 8-Containing Secretory Compartment
Fabienne Paumet,Joëlle Le Mao,Sophie Martin,Thierry Galli,Bernard David,Ulrich Blank,Michèle Roa +6 more
TL;DR: Results are the first demonstration that the nonneuronal VAMP8 isoform, originally localized on early endosomes, is present in a regulated secretory compartment and suggest that syntaxin 4, SNAP23, and Vamp8 may be involved in regulation of mast cell exocytosis.
Journal ArticleDOI
SNARE Protein Mimicry by an Intracellular Bacterium
Cédric Delevoye,Michael Nilges,Pierre Dehoux,Fabienne Paumet,Stéphanie Perrinet,Alice Dautry-Varsat,Agathe Subtil +6 more
TL;DR: SNARE-like motifs in the inclusion protein IncA are identified, which are conserved among most Chlamydia species and demonstrate for the first time mimicry of the SNARE motif by a bacterium.
Journal Article
Involvement of the ras-like GTPase rab3d in RBL-2H3 mast cell exocytosis following stimulation via high affinity IgE receptors (Fc epsilonRI).
TL;DR: This study investigated the role of the small GTPases of the rab3 subfamily in the regulated exocytosis following stimulation of rat basophilic leukemia cells (RBL-2H3), and found that rab3d interferes with a rate-limiting step in Fc epsilonRI-stimulated exocyTosis.