F
Falk Hildebrand
Researcher at Norwich University
Publications - 87
Citations - 16383
Falk Hildebrand is an academic researcher from Norwich University. The author has contributed to research in topics: Microbiome & Metagenomics. The author has an hindex of 32, co-authored 74 publications receiving 11776 citations. Previous affiliations of Falk Hildebrand include Norwich Research Park & University of Sussex.
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Journal ArticleDOI
The gut microbiome is associated with behavioural task in honey bees
Julia C. Jones,Julia C. Jones,Carmelo Fruciano,Carmelo Fruciano,J. Marchant,Falk Hildebrand,Sofia K. Forslund,Peer Bork,Philipp Engel,William O. H. Hughes +9 more
TL;DR: The authors' results show that some core members of the unique honey bee gut bacterial community are represented in different relative abundances in bees performing different behavioural tasks, and suggest an influence of task-related local environment exposure and diet on the honey bees gut microbial community.
Journal ArticleDOI
RTK: efficient rarefaction analysis of large datasets
TL;DR: A software package for rarefaction analysis of large count matrices, as well as estimation and visualization of diversity, richness and evenness, designed for ease of use and operating at least 7x faster than existing solutions, despite requiring 10x less memory.
Journal ArticleDOI
Caspase deficiency alters the murine gut microbiome.
Brigitta M. Brinkman,Falk Hildebrand,Malgorzata Kubica,D Goosens,J Del Favero,Wim Declercq,Jeroen Raes,Peter Vandenabeele +7 more
TL;DR: The authors' data point toward an intricate relationship between these caspases and the composition of the murine gut microflora, particularly the Firmicutes and Bacteroidetes phyla, when comparing Casp-1, -7 and -3 knockout mice with wild-type mice.
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Gut microbiota affects sensitivity to acute DSS-induced colitis independently of host genotype.
Brigitta M. Brinkman,Anne A. M. J. Becker,Rene B. Ayiseh,Falk Hildebrand,Jeroen Raes,Geert Huys,Peter Vandenabeele +6 more
TL;DR: C cohousing experiments revealed that the colitogenic activity of the WT microbiota is transferable to Casp3/11−/− mice and that Prevotella species are likely to be involved and underscore the need for in-depth studies of the bilateral interaction of host genes and microbiota to gain insight into the mechanisms of disease pathogenesis.
Journal ArticleDOI
Disentangling the impact of environmental and phylogenetic constraints on prokaryotic within-species diversity.
Oleksandr M. Maistrenko,Daniel R Mende,Mechthild Luetge,Falk Hildebrand,Thomas Schmidt,Simone S. Li,João Domingos Rodrigues,Christian von Mering,Luis Pedro Coelho,Jaime Huerta-Cepas,Shinichi Sunagawa,Peer Bork +11 more
TL;DR: The global principles of pangenome evolution are explored, the influence of habitat, and phylogenetic inertia on the evolution of pangsenomes are quantified, and criteria governing species ubiquity and habitat specificity are identified.