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Felix Sommer
Researcher at University of Kiel
Publications - 65
Citations - 6622
Felix Sommer is an academic researcher from University of Kiel. The author has contributed to research in topics: Gut flora & ASDEX Upgrade. The author has an hindex of 24, co-authored 53 publications receiving 4871 citations. Previous affiliations of Felix Sommer include Max Planck Society & University of Gothenburg.
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The gut microbiota — masters of host development and physiology
TL;DR: The gut microbiota has a beneficial role during normal homeostasis, modulating the host's immune system as well as influencing host development and physiology, including organ development and morphogenesis, and host metabolism.
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The resilience of the intestinal microbiota influences health and disease
TL;DR: The concepts and mechanisms of microbial resilience against dietary, antibiotic or bacteriotherapy-induced perturbations and the implications for human health are discussed.
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Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota
Jun Wang,Louise B. Thingholm,Jurgita Skiecevičienė,Philipp Rausch,Philipp Rausch,Martin Kummen,Johannes R. Hov,Frauke Degenhardt,Femke-Anouska Heinsen,Malte C. Rühlemann,Silke Szymczak,Kristian Holm,Tõnu Esko,Jun Sun,Mihaela Pricop-Jeckstadt,Samer Al-Dury,Pavol Bohov,Jörn Bethune,Felix Sommer,David Ellinghaus,Rolf K. Berge,Rolf K. Berge,Matthias Hübenthal,Manja Koch,Karin Schwarz,Gerald Rimbach,Patricia Hübbe,Wei-Hung Pan,Raheleh Sheibani-Tezerji,Robert Häsler,P Rosenstiel,Mauro D'Amato,Mauro D'Amato,Katja Cloppenborg-Schmidt,Sven Künzel,Matthias Laudes,Hanns-Ulrich Marschall,Wolfgang Lieb,Ute Nöthlings,Tom H. Karlsen,John F. Baines,John F. Baines,Andre Franke +42 more
TL;DR: Genome-wide significant associations for overall microbial variation and individual taxa at multiple genetic loci identify other important points of host–microbe intersection, notably several disease susceptibility genes and sterol metabolism pathway components.
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The composition of the gut microbiota shapes the colon mucus barrier
Hedvig E. Jakobsson,Ana M. Rodríguez-Piñeiro,André Schütte,Anna Ermund,Preben Boysen,Mats Bemark,Mats Bemark,Felix Sommer,Fredrik Bäckhed,Gunnar C. Hansson,Malin E. V. Johansson +10 more
TL;DR: The study shows that bacteria and their community structure affect mucus barrier properties in ways that can have implications for health and disease and highlights that genetically identical animals housed in the same facility can have rather distinct microbiotas and barrier structures.
Journal ArticleDOI
Microbiota-induced obesity requires farnesoid X receptor
Ava Parséus,Nina Sommer,Felix Sommer,Robert Caesar,Antonio Molinaro,Marcus Ståhlman,Thomas U. Greiner,Rosie Perkins,Fredrik Bäckhed,Fredrik Bäckhed +9 more
TL;DR: The results indicate that the gut microbiota promotes diet-induced obesity and associated phenotypes through FXR, and that FXR may contribute to increased adiposity by altering the microbiota composition.