F
Florent Malard
Researcher at University of Nantes
Publications - 22
Citations - 1149
Florent Malard is an academic researcher from University of Nantes. The author has contributed to research in topics: Transplantation & Hematopoietic stem cell transplantation. The author has an hindex of 14, co-authored 22 publications receiving 887 citations.
Papers
More filters
Journal ArticleDOI
Revised diagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a new classification from the European Society for Blood and Marrow Transplantation
M. Mohty,Florent Malard,M. Abecassis,Erik Aerts,Ahmed Alaskar,M Aljurf,Mutlu Arat,Peter Bader,Frédéric Baron,Ali Bazarbachi,Didier Blaise,Fabio Ciceri,Selim Corbacioglu,J.-H. Dalle,Fiona L Dignan,Takahiro Fukuda,Anne Huynh,Tamás Masszi,Mauricette Michallet,Arnon Nagler,Mairead NiChonghaile,S. Okamoto,A Pagliuca,C Peters,Finn Bo Petersen,Paul G. Richardson,Tapani Ruutu,Bipin N. Savani,E. Wallhult,Ibrahim Yakoub-Agha,R. F. Duarte,Enric Carreras +31 more
TL;DR: A new definition for diagnosis, and a severity-grading system for SOS/VOD in adult patients, are proposed on behalf of the European Society for Blood and Marrow Transplantation.
Journal ArticleDOI
Sinusoidal obstruction syndrome/veno-occlusive disease: Current situation and perspectives - A position statement from the European Society for Blood and Marrow Transplantation (EBMT)
M. Mohty,Florent Malard,M. Abecassis,Erik Aerts,As. Alaskar,M Aljurf,Mutlu Arat,Peter Bader,Frédéric Baron,Ali Bazarbachi,Didier Blaise,Fabio Ciceri,Selim Corbacioglu,J.-H. Dalle,R. F. Duarte,Takahiro Fukuda,Anne Huynh,Tamás Masszi,Mauricette Michallet,Arnon Nagler,Mairead NiChonghaile,T. Pagluica,C Peters,Fb. Petersen,P. G. Richardson,Tapani Ruutu,B.N. Savani,Elisabeth Wallhult,Ibrahim Yakoub-Agha,Enric Carreras +29 more
TL;DR: This review aims to highlight, on behalf of the European Society for Blood and Marrow Transplantation, the current knowledge on SOS/VOD pathophysiology, risk factors, diagnosis and treatments.
Journal ArticleDOI
IL-7 receptor influences anti-TNF responsiveness and T cell gut homing in inflammatory bowel disease.
Lyssia Belarif,Richard Danger,Laetitia Kermarrec,Véronique Nerrière-Daguin,Sabrina Pengam,Tony Durand,Caroline Mary,Elise Kerdreux,Vanessa Gauttier,Aneta Kucik,Virginie Thepenier,Jerome Martin,Christie Chang,Adeeb Rahman,Nina Salabert-Le Guen,Cécile Braudeau,Ahmed Abidi,Ahmed Abidi,Grégoire David,Florent Malard,Celine Takoudju,Bernard Martinet,Nathalie Gérard,Isabelle Neveu,Michel Neunlist,Emmanuel Coron,Thomas T. MacDonald,Pierre Desreumaux,Hoa-Le Mai,Stéphanie Le Bas-Bernardet,Jean-François Mosnier,Miriam Merad,Régis Josien,Sophie Brouard,Jean-Paul Soulillou,Gilles Blancho,Arnaud Bourreille,Philippe Naveilhan,Bernard Vanhove,Nicolas Poirier +39 more
TL;DR: Key transcripts of the IL-7 receptor (IL-7R) pathway are accumulated in inflamed colon tissues of severe CD and UC patients not responding to either immunosuppressive/corticosteroid, anti-TNF, or anti-α4β7 therapies, and point to IL- 7R as a relevant therapeutic target and potential biomarker to fill an unmet need in clinical IBD detection and treatment.
Journal ArticleDOI
Features of Epstein-Barr Virus (EBV) reactivation after reduced intensity conditioning allogeneic hematopoietic stem cell transplantation.
Zinaida Peric,Xavier Cahu,Patrice Chevallier,Eolia Brissot,Florent Malard,Thierry Guillaume,Jacques Delaunay,Sameh Ayari,V. Dubruille,S. Le Gouill,Béatrice Mahé,Thomas Gastinne,N. Blin,Beatrice Saulquin,J-L Harousseau,Philippe Moreau,Noel-Jean Milpied,M. Coste-Burel,Berthe-Marie Imbert-Marcille,Mohamad Mohty +19 more
TL;DR: It is concluded that patients undergoing RIC allo-HSCT using anti-thymocyte globulin as part of the preparative regimen are at higher risk for EBV reactivation, but quantitative monitoring of EBV viral load by PCR and preemptive rituximab therapy allowed for significantly reducing the risk ofEBV-related LPD.
Journal ArticleDOI
Increased Th17/Treg ratio in chronic liver GVHD.
Florent Malard,Céline Bossard,Eolia Brissot,Patrice Chevallier,Thierry Guillaume,Jacques Delaunay,Jean-François Mosnier,Philippe Moreau,Marc Grégoire,Béatrice Gaugler,Mohamad Mohty +10 more
TL;DR: Evidence is provided for an infiltration by Th 17 cells in the liver of patients with cGVHD and an increased Th17/Treg ratio, suggesting a defect in the regulatory mechanism driven by Treg cells or an inappropriate activation of effectors cells, especially Th17 cells, or both mechanisms, in human liver cGV HD.