A
Arnaud Bourreille
Researcher at University of Nantes
Publications - 149
Citations - 8015
Arnaud Bourreille is an academic researcher from University of Nantes. The author has contributed to research in topics: Inflammatory bowel disease & Ulcerative colitis. The author has an hindex of 37, co-authored 128 publications receiving 6740 citations. Previous affiliations of Arnaud Bourreille include Centre Hospitalier Universitaire de Nantes & French Institute of Health and Medical Research.
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Journal ArticleDOI
Butyrate inhibits inflammatory responses through NFκB inhibition: implications for Crohn's disease
Jean-Pierre Segain,D. Raingeard de la Blétière,Arnaud Bourreille,V. Leray,Nadine Gervois,Carlos Rosales,L Ferrier,C. Bonnet,Hervé M. Blottière,J. P. Galmiche +9 more
TL;DR: Butyrate decreases proinflammatory cytokine expression via inhibition of NFκB activation and IκBα degradation and these anti-inflammatory properties provide a rationale for assessing butyrate in the treatment of CD.
Journal ArticleDOI
Ciclosporin versus infliximab in patients with severe ulcerative colitis refractory to intravenous steroids: a parallel, open-label randomised controlled trial
David Laharie,Arnaud Bourreille,Julien Branche,Matthieu Allez,Yoram Bouhnik,Jérôme Filippi,Frank Zerbib,Guillaume Savoye,Maria Nachury,Jacques Moreau,Jean-Charles Delchier,Jacques Cosnes,Elena Ricart,Olivier Dewit,Antonio López-Sanromán,Jean-Louis Dupas,Franck Carbonnel,Gilles Bommelaer,Benoit Coffin,Xavier Roblin,Gert Van Assche,Maria Esteve,Martti Färkkilä,Martti Färkkilä,Javier P. Gisbert,Philippe Marteau,Stéphane Nahon,Martine De Vos,Denis Franchimont,Jean Yves Mary,Jean-Frederic Colombel,Marc Lémann +31 more
TL;DR: Ciclosporin was not more effective than infliximab in patients with acute severe ulcerative colitis refractory to intravenous steroids and should be guided by physician and centre experience.
Journal ArticleDOI
Ineffectiveness of Lactobacillus johnsonii LA1 for prophylaxis of postoperative recurrence in Crohn’s disease: a randomised, double blind, placebo controlled GETAID trial
P. Marteau,Marc Lémann,P. Seksik,D. Laharie,J.-F. Colombel,Yoram Bouhnik,Guillaume Cadiot,Soulé Jc,Arnaud Bourreille,Etienne Henry Metman,Eric Lerebours,F. Carbonnel,J.L. Dupas,Michel Veyrac,Benoit Coffin,J. Moreau,V. Abitbol,S. Blum-Sperisen,Jean-Yves Mary +18 more
TL;DR: The probiotic strain L johnsonii LA1 (4×109 cfu/day) did not have a sufficient effect, if any, to prevent endoscopic recurrence of Crohn’s disease.
Journal ArticleDOI
Infliximab plus azathioprine for steroid-dependent Crohn's disease patients: a randomized placebo-controlled trial.
Marc Lémann,Jean Yves Mary,Bernard Duclos,Michel Veyrac,Jean Louis Dupas,Jean Charles Delchier,David Laharie,Jacques Moreau,Guillaume Cadiot,Laurence Picon,Arnaud Bourreille,Iradj Sobahni,Jean-Frederic Colombel +12 more
TL;DR: Infliximab plus AZA/6-MP is more effective than AZA or 6-mercaptopurine alone in steroid-dependent Crohn's disease patients.
Journal ArticleDOI
Enteric Glia Regulate Intestinal Barrier Function and Inflammation Via Release of S-Nitrosoglutathione
Tor C. Savidge,Tor C. Savidge,Paul Newman,Charalabos Pothoulakis,A. Ruhl,Michel Neunlist,Arnaud Bourreille,Roger D. Hurst,Michael V. Sofroniew +8 more
TL;DR: Enteric glia share the ability of astrocytes to regulate tight-junction integrity, and cellular interactions comparable with those maintaining blood-brain barrier function also regulate epithelial permeability at mucosal surfaces.