F
Francisco J. Campos-Laborie
Researcher at University of Salamanca
Publications - 14
Citations - 949
Francisco J. Campos-Laborie is an academic researcher from University of Salamanca. The author has contributed to research in topics: Gene & Protein family. The author has an hindex of 8, co-authored 13 publications receiving 452 citations. Previous affiliations of Francisco J. Campos-Laborie include Wellcome Trust/Cancer Research UK Gurdon Institute & Spanish National Research Council.
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Journal ArticleDOI
A reference map of the human binary protein interactome
Katja Luck,Dae-Kyum Kim,Luke Lambourne,Kerstin Spirohn,Bridget E. Begg,Wenting Bian,Ruth Brignall,Tiziana M. Cafarelli,Francisco J. Campos-Laborie,Benoit Charloteaux,Dong-Sic Choi,Atina G. Cote,Meaghan Daley,Steven Deimling,Alice Desbuleux,Amélie Dricot,Marinella Gebbia,Madeleine F. Hardy,Nishka Kishore,Jennifer J. Knapp,István Kovács,István Kovács,Irma Lemmens,Irma Lemmens,Miles W. Mee,Joseph C. Mellor,Carl Pollis,Carles Pons,Aaron Richardson,Sadie Schlabach,Bridget Teeking,Anupama Yadav,Mariana Babor,Dawit Balcha,Omer Basha,Christian Bowman-Colin,Suet-Feung Chin,Soon Gang Choi,Claudia Colabella,Georges Coppin,Cassandra D’Amata,David De Ridder,Steffi De Rouck,Steffi De Rouck,Miquel Duran-Frigola,Hanane Ennajdaoui,Florian Goebels,Liana Goehring,Anjali Gopal,Ghazal Haddad,Elodie Hatchi,Mohamed Helmy,Yves Jacob,Yves Jacob,Yoseph Kassa,Serena Landini,Roujia Li,Natascha van Lieshout,Andrew MacWilliams,Dylan Markey,Joseph N. Paulson,Joseph N. Paulson,Sudharshan Rangarajan,John Rasla,Ashyad Rayhan,Thomas Rolland,Adriana San-Miguel,Yun Shen,Dayag Sheykhkarimli,Gloria M. Sheynkman,Eyal Simonovsky,Murat Tasan,Alexander O. Tejeda,Vincent Tropepe,Jean-Claude Twizere,Yang Wang,Robert J. Weatheritt,Jochen Weile,Yu Xia,Yu Xia,Xinping Yang,Esti Yeger-Lotem,Quan Zhong,Patrick Aloy,Gary D. Bader,Javier De Las Rivas,Suzanne Gaudet,Tong Hao,Janusz Rak,Jan Tavernier,Jan Tavernier,David E. Hill,Marc Vidal,Frederick P. Roth,Michael A. Calderwood +94 more
TL;DR: The utility of HuRI is demonstrated in identifying the specific subcellular roles of protein–protein interactions and in identifying potential molecular mechanisms that might underlie tissue-specific phenotypes of Mendelian diseases.
Journal ArticleDOI
APID database: redefining protein-protein interaction experimental evidences and binary interactomes.
Diego Alonso-López,Francisco J. Campos-Laborie,Miguel A. Gutiérrez,Luke Lambourne,Michael A. Calderwood,Marc Vidal,Javier De Las Rivas +6 more
TL;DR: An update of APID database is performed including a redefinition of several key properties of the PPIs to provide a more precise data integration and to avoid false duplicated records.
Journal ArticleDOI
Matrix-Gla protein promotes osteosarcoma lung metastasis and associates with poor prognosis.
Carolina Zandueta,Cristina Ormazábal,Naiara Perurena,Susana Martínez-Canarias,Marta Zalacain,Mikel San Julián,Agamemnon E. Grigoriadis,Karmele Valencia,Francisco J. Campos-Laborie,Javier De Las Rivas,Silvestre Vicent,Ana Patiño-García,Fernando Lecanda +12 more
TL;DR: MGP, encoding matrix‐Gla protein (MGP), a non‐collagenous matrix protein previously associated with the inhibition of arterial calcification, represents a novel adverse prognostic factor and a potential therapeutic target in OS.
Journal ArticleDOI
Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression
Carolina F. Ruivo,Nuno Bastos,Bárbara Adem,Inês A. Batista,Cecília Durães,Carlos A. Melo,Stephanie Anais Castaldo,Francisco J. Campos-Laborie,Pedro Moutinho-Ribeiro,B Morão,Ana Costa-Pinto,Soraia Silva,Hugo Osório,Sergio Ciordia,José Luis Costa,David W. Goodrich,Bruno Cavadas,Luísa Pereira,Tony Kouzarides,Guilherme Macedo,Rui Maio,Fátima Carneiro,Marília Cravo,Raghu Kalluri,José Carlos Machado,Sonia A. Melo +25 more
TL;DR: PDAC tumours establish a cooperation network mediated by EVs that is led by CSC and agrin, which allows tumours to adapt and thrive, and targeting agrin could make targeted therapy possible for patients with PDAC.
Posted ContentDOI
A reference map of the human protein interactome
Katja Luck,Dae-Kyum Kim,Dae-Kyum Kim,Luke Lambourne,Kerstin Spirohn,Bridget E. Begg,Wenting Bian,Ruth Brignall,Tiziana M. Cafarelli,Francisco J. Campos-Laborie,Benoit Charloteaux,Dong-Sic Choi,Atina G. Cote,Atina G. Cote,Meaghan Daley,Steven Deimling,Alice Desbuleux,Alice Desbuleux,Amélie Dricot,Marinella Gebbia,Marinella Gebbia,Madeleine F. Hardy,Nishka Kishore,Nishka Kishore,Jennifer J. Knapp,Jennifer J. Knapp,István Kovács,István Kovács,István Kovács,Irma Lemmens,Irma Lemmens,Miles W. Mee,Joseph C. Mellor,Joseph C. Mellor,Carl Pollis,Carles Pons,Aaron Richardson,Sadie Schlabach,Bridget Teeking,Anupama Yadav,Mariana Babor,Mariana Babor,Dawit Balcha,Omer Basha,Christian Bowman-Colin,Suet-Feung Chin,Soon Gang Choi,Claudia Colabella,Georges Coppin,Georges Coppin,Cassandra D’Amata,David De Ridder,Steffi De Rouck,Steffi De Rouck,Miquel Duran-Frigola,Hanane Ennajdaoui,Hanane Ennajdaoui,Florian Goebels,Liana Goehring,Anjali Gopal,Anjali Gopal,Ghazal Haddad,Ghazal Haddad,Elodie Hatchi,Mohamed Helmy,Yves Jacob,Yves Jacob,Yoseph Kassa,Serena Landini,Roujia Li,Roujia Li,Natascha van Lieshout,Natascha van Lieshout,Andrew MacWilliams,Dylan Markey,Joseph N. Paulson,Joseph N. Paulson,Sudharshan Rangarajan,John Rasla,Ashyad Rayhan,Ashyad Rayhan,Thomas Rolland,Adriana San-Miguel,Yun Shen,Dayag Sheykhkarimli,Dayag Sheykhkarimli,Gloria M. Sheynkman,Eyal Simonovsky,Murat Tasan,Murat Tasan,Alexander O. Tejeda,Jean-Claude Twizere,Yang Wang,Robert J. Weatheritt,Jochen Weile,Jochen Weile,Yu Xia,Yu Xia,Xinping Yang,Esti Yeger-Lotem,Quan Zhong,Quan Zhong,Patrick Aloy,Gary D. Bader,Javier De Las Rivas,Suzanne Gaudet,Tong Hao,Janusz Rak,Jan Tavernier,Jan Tavernier,Vincent Tropepe,David E. Hill,Marc Vidal,Frederick P. Roth,Frederick P. Roth,Frederick P. Roth,Michael A. Calderwood +116 more
TL;DR: The first human “all-by-all” binary reference interactome map, or HuRI, is presented and it is demonstrated the use of HuRI in identifying specific subcellular roles of PPIs and protein function modulation via splicing during brain development.