F
Frédérique Courant
Researcher at University of Montpellier
Publications - 46
Citations - 1887
Frédérique Courant is an academic researcher from University of Montpellier. The author has contributed to research in topics: Metabolomics & Biology. The author has an hindex of 24, co-authored 41 publications receiving 1546 citations. Previous affiliations of Frédérique Courant include Université Nantes Angers Le Mans & École Normale Supérieure.
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Journal ArticleDOI
Assessment of circulating sex steroid levels in prepubertal and pubertal boys and girls by a novel ultrasensitive gas chromatography-tandem mass spectrometry method
Frédérique Courant,Lise Aksglaede,Jean-Philippe Antignac,Fabrice Monteau,Kaspar Sørensen,Anna-Maria Andersson,Niels E. Skakkebæk,Anders Juul,Bruno Le Bizec +8 more
TL;DR: Use of an accurate and sensitive method found significantly higher levels of estrogens as well as androgen metabolites in prepubertal girls compared with age-matched boys, which may contribute to their earlier onset of puberty including pubic hair development.
Journal ArticleDOI
Human testis steroidogenesis is inhibited by phthalates.
Christèle Desdoits-Lethimonier,Océane Albert,Océane Albert,B. Le Bizec,Elisabeth Perdu,Daniel Zalko,Frédérique Courant,Laurianne Lesné,Laurianne Lesné,Francois Guille,Nathalie Dejucq-Rainsford,Nathalie Dejucq-Rainsford,Bernard Jégou,Bernard Jégou +13 more
TL;DR: The first evidence that DEHP and MEHP can inhibit testosterone production in the adult human testis is provided, consistent with recent epidemiological findings of an inverse correlation between exposure to MEHP and testosterone concentrations.
Journal ArticleDOI
Diclofenac in the marine environment: A review of its occurrence and effects.
TL;DR: The findings highlight the scarcity of available data on the occurrence and effects of DCF in marine ecosystems, and the need for further data acquisition to assess the risks associated with the presence of this compound in the environment.
Journal ArticleDOI
Development of a metabolomic approach based on liquid chromatography-high resolution mass spectrometry to screen for clenbuterol abuse in calves.
Frédérique Courant,Gaud Pinel,Emmanuelle Bichon,Fabrice Monteau,Jean-Philippe Antignac,Bruno Le Bizec +5 more
TL;DR: An untargeted metabolomic approach based on liquid chromatography coupled to high resolution mass spectrometry measurements was developed and made it possible to highlight metabolic modifications in urine consecutively to a clenbuterol administration.
Journal ArticleDOI
Can we trust untargeted metabolomics? Results of the metabo-ring initiative, a large-scale, multi-instrument inter-laboratory study.
Jean-Charles Martin,Mathieu Maillot,Gerard Mazerolles,Alexandre Verdu,Bernard Lyan,Carole Migné,Catherine Defoort,Cécile Canlet,Christophe Junot,Claude Guillou,Claudine Manach,Daniel J. Jacob,Delphine Jouan-Rimbaud Bouveresse,Estelle Paris,Estelle Pujos-Guillot,Fabien Jourdan,Franck Giacomoni,Frédérique Courant,Gaëlle Favé,Gwénaëlle Le Gall,Hubert Chassaigne,Jean-Claude Tabet,Jean-François Martin,Jean-Philippe Antignac,Laetitia Shintu,Marianne Defernez,Mark Philo,Marie-Cécile Alexandre Gouaubau,Marie Josephe Amiot-Carlin,Mathilde Bossis,Mohamed N. Triba,Nathali Stojilkovic,Nathalie Banzet,Roland Molinié,Romain Bott,Sophie Goulitquer,Stefano Caldarelli,Douglas N. Rutledge +37 more
TL;DR: In conclusion, untargeted metabolomics analyses report consistent information within and across instruments of various technologies, even without prior standardisation.