Fu-Ying Qin

TL;DR: Biological assessments reveal that compounds (+)-1 and 7 could significantly protect SH-SY5Y cells from glutamate-induced neural excitotoxicity.

TL;DR: Three new polyynes, named choushenpilosulynes A–C (1–3), were isolated from an 85% aqueous EtOH extract of the roots of Codonopsis pilosula cultivated in Xundian County of Yunnan province, China, and biological evaluation shows that all the compounds can inhibit the expression of the squalene monooxygenase gene in HepG2 cells, suggesting that these compounds may be involved in lipid metabolism.

TL;DR: In vivo anti-inflammatory activities of (-)-2 were performed against acute lung injury in mice and site-directed mutagenesis identified His351 as a COX-2 active site.

TL;DR: Six new meroterpenoids, australeols A-F (1-6), together with nineteen known compounds (7-25), were isolated from the fruiting bodies of Ganoderma Australe, revealing potent neuroprotective activities in glutamate-stimulated SH-SY5Y cells.

TL;DR: Seven compounds, including two pairs of new meroterpenoids, (+)- and (−)-gancochlearol C, together with four known meroter penoids were isolated from the aqueous EtOH extract of the fruiting bodies of Ganoderma cochlear, and their structures were determined by spectroscopic data.