F
Fulvio Mavilio
Researcher at University of Modena and Reggio Emilia
Publications - 228
Citations - 20283
Fulvio Mavilio is an academic researcher from University of Modena and Reggio Emilia. The author has contributed to research in topics: Genetic enhancement & Viral vector. The author has an hindex of 68, co-authored 227 publications receiving 19200 citations. Previous affiliations of Fulvio Mavilio include Paris Descartes University & Vita-Salute San Raffaele University.
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Journal ArticleDOI
Clonal analysis of stably transduced human epidermal stem cells in culture.
Monica Beatriz Mathor,Giuliana Ferrari,Elena Dellambra,Michele Cilli,Fulvio Mavilio,Ranieri Cancedda,M. De Luca +6 more
TL;DR: In this paper, normal human keratinocytes were transduced with retroviral constructs expressing a bacterial beta-galactosidase (beta-gal) gene or a human interleukin-6 (hIL-6) cDNA under control of a long terminal repeat.
Journal ArticleDOI
Retinoic acid induces stage-specific antero-posterior transformation of rostral central nervous system
Antonio Simeone,Virginia Avantaggiato,Maria Cristina Moroni,Fulvio Mavilio,Claudio Arra,Franco Cotelli,Vincenzo Nigro,Dario Acampora +7 more
TL;DR: The analysis indicates that RA interferes with the correct definition of both planar and vertical morphogenetic signals at specific developmental stages by affecting gene expression in the regions which are likely either to produce or to respond to these signals.
Journal ArticleDOI
Long-term microdystrophin gene therapy is effective in a canine model of Duchenne muscular dystrophy.
Caroline Le Guiner,Laurent Servais,Marie Montus,Thibaut Larcher,Bodvael Fraysse,Sophie Moullec,M. Allais,Virginie François,Maeva Dutilleul,Alberto Malerba,Taeyoung Koo,Jean-Laurent Thibaut,B. Matot,Marie Devaux,Johanne Le Duff,Jack-Yves Deschamps,Inès Barthélémy,Inès Barthélémy,Stéphane Blot,Stéphane Blot,Isabelle Testault,Karim Wahbi,Stéphane Ederhy,Samia Martin,Philippe Veron,Christophe Georger,Takis Athanasopoulos,Takis Athanasopoulos,Takis Athanasopoulos,Carole Masurier,Federico Mingozzi,Pierre G. Carlier,Bernard Gjata,Jean-Yves Hogrel,Oumeya Adjali,Fulvio Mavilio,Thomas Voit,Philippe Moullier,Philippe Moullier,George Dickson +39 more
TL;DR: It is shown that locoregional and systemic delivery of a rAAV2/8 vector expressing a canine microdystrophin (cMD1) is effective in restoring dyStrophin expression and stabilizing clinical symptoms in studies performed on a total of 12 treated golden retriever muscular dystrophy dogs.
Clonal analysis of stably transduced human epidermal stem cells in culture. [5YIF: 10.60; Citations: 123]
Mb Mathor,Giuliana Ferrari,Elena Dellambra,Michele Cilli,Fulvio Mavilio,Ranieri Cancedda,Michele De Luca +6 more
TL;DR: The possibility of specifying the level of transgene expression and its permanence in a homogeneous clone of stem cell origin opens new perspectives in the long-term treatment of genetic disorders.
Journal ArticleDOI
High-definition mapping of retroviral integration sites identifies active regulatory elements in human multipotent hematopoietic progenitors
Claudia Cattoglio,Danilo Pellin,Ermanno Rizzi,Giulietta Maruggi,Giorgio Corti,Francesca Miselli,Daniela Sartori,Alessandro Guffanti,Clelia Di Serio,Alessandro Ambrosi,Gianluca De Bellis,Fulvio Mavilio +11 more
TL;DR: High-definition MLV integration maps provide a rational basis for predicting genotoxic risks in gene therapy and a new tool for genomewide identification of promoters and regulatory elements controlling hematopoietic stem and progenitor cell functions.