Gail E. Hafley

TL;DR: Electrophysiologically guided antiarrhythmic therapy with implantable defibrillators, but not with antiarrHythmic drugs, reduces the risk of sudden death in high-risk patients with coronary disease and asymptomatic, unsustained ventricular tachycardia.

TL;DR: Among patients with unstable angina or myocardial infarction without ST-segment elevation, prasugrel did not significantly reduce the frequency of the primary end point, as compared with clopidogrel, and similar risks of bleeding were observed.

TL;DR: Electrophysiologic testing in patients who had coronary artery disease, a left ventricular ejection fraction of 40 percent or less, and asymptomatic, unsustained ventricular tachycardia found them to have a significantly lower risk of sudden death or cardiac arrest and lower overall mortality than similar patients with inducible sustained tachyarrhythmias.

TL;DR: Risk of sudden death in patients with coronary disease depends on multiple variables in addition to ejection fraction, and the model demonstrates that patients whose only risk factor is EF < or =30% have a predicted 2-year arrhythmic death risk <5%.

TL;DR: Endoscopic vein-graft harvesting is independently associated with vein- graft failure and adverse clinical outcomes and Randomized clinical trials are needed to further evaluate the safety and effectiveness of this harvesting technique.