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Gary Rhodes

Researcher at Scripps Health

Publications -  35
Citations -  4175

Gary Rhodes is an academic researcher from Scripps Health. The author has contributed to research in topics: Antigen & Virus. The author has an hindex of 19, co-authored 35 publications receiving 4079 citations. Previous affiliations of Gary Rhodes include University of California, Davis & Wisconsin Alumni Research Foundation.

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Heterologous protection against influenza by injection of DNA encoding a viral protein

TL;DR: To generate a viral antigen for presentation to the immune system without the limitations of direct peptide delivery or viral vectors, plasmid DNA encoding influenza A nucleop protein was injected into the quadriceps of BALB/c mice and resulted in the generation of nucleoprotein-specific CTLs.
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Susceptibility to rheumatoid arthritis maps to a T-cell epitope shared by the HLA-Dw4 DR beta-1 chain and the Epstein-Barr virus glycoprotein gp110

TL;DR: An analysis of protein and DNA databases revealed that the Epstein-Barr virus glycoprotein gp110 contains the sequence QKRAAQRAA, which is highly homologous to the rheumatoid arthritis susceptibility determinant.
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Self-replicating Semliki Forest virus RNA as recombinant vaccine.

TL;DR: It is concluded that the self-replicative recombinant SFV RNA may be quite useful as a nucleic acid vaccine.
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Self-replicative RNA vaccines elicit protection against influenza A virus, respiratory syncytial virus, and a tickborne encephalitis virus.

TL;DR: This study addressed the possibility of using the recombinant alpha virus RNA molecule, which replicates in the cytoplasm of transfected cells, as a novel approach for genetic vaccination.
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Long-Term Anti-Nucleoprotein Cellular and Humoral Immunity Is Induced by Intramuscular Injection of Plasmid DNA Containing NP Gene

TL;DR: It is shown that a single intramuscular injection of a small dose of nucleoprotein plasmid DNA generates nucleop protein-specific cellular and humoral immune responses that last 1 year that are associated with the CD8+ subpopulation of T cells.