Gennaro D'Amato

TL;DR: Clinical and aerobiologic studies show that the pollen map of Europe is changing also as a result of cultural factors and greater international travel, and studies on allergen‐carrying paucimicronic or submicronic airborne particles, which penetrate deep into the lung, are having a relevant impact on understanding of pollinosis and its distribution throughout Europe.

TL;DR: Global warming is expected to affect the start, duration, and intensity of the pollen season, and the rate of asthma exacerbations due to air pollution, respiratory infections, and/or cold air inhalation, and other conditions on the other hand.

TL;DR: A more severe immunoglobulin (Ig) E-mediated response to aeroallergens and airway inflammation could account for increasing prevalence of allergic respiratory diseases in polluted urban areas.

TL;DR: Climate change might induce negative effects on respiratory allergic diseases, in particular, the increased length and severity of the pollen season, the higher occurrence of heavy precipitation events and the increasing frequency of urban air pollution episodes suggest that environmental risk factors will have a stronger effect in the following decades.

TL;DR: Next-generation guidelines for the pharmacologic treatment of allergic rhinitis were developed by using existing GRADE-based guidelines forThe disease, real-world evidence provided by mobile technology, and additive studies (allergen chamber studies) to refine the MACVIA algorithm.